Palbociclib (monohydrochloride)

Palbociclib (monohydrochloride)
Product Description

Palbociclib (monohydrochloride) is a highly selective inhibitor of cyclin-dependent kinases 4 and 6 (CDK4/6), which play a crucial role in regulating cell cycle progression. By inhibiting CDK4/6, Palbociclib effectively arrests cell cycle progression, particularly in cancer cells that rely on CDK4/6 activity for proliferation.

Shanghai Haoyuan ChemExpress Co., Ltd.

  • Country/Region:
    China
  • On CPHI since:
    2022
  • Certificates:
    3
  • Employees:
    1000 - 4999
Company types
CMO/CDMO
Contract Research Organisation (CRO)
Primary activities
Analytical Services
Contract Manufacturer
Contract Research Organisation
Custom Manufacturing/Custom Synthesis
Generic APIs producer
Intermediates Manufacturer
Specifications
  • CAS Registry Number
    827022-32-2
  • Details
    Palbociclib (PD-0332991) HCl is a highly selective CDK4/6 inhibitor with IC50 values of 11 nM and 16 nM for CDK4 and CDK6, respectively, in cell-free assays. It shows no inhibitory activity against CDK1/2/5, EGFR, FGFR, PDGFR, InsR, and others. Phase 3.

Shanghai Haoyuan ChemExpress Co., Ltd.

  • Country/Region:
    China
  • On CPHI since:
    2022
  • Certificates:
    3
  • Employees:
    1000 - 4999
Company types
CMO/CDMO
Contract Research Organisation (CRO)
Primary activities
Analytical Services
Contract Manufacturer
Contract Research Organisation
Custom Manufacturing/Custom Synthesis
Generic APIs producer
Intermediates Manufacturer

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