PEGylation Services

JenKem Technology’s dedicated and experienced technical support group can help you identify the right high quality PEG derivatives for your pegylation needs. Currently JenKem Technology provides two pegylation service models:

Service model 1. PEGylation services provided as a regular end-product.
JenKem Technology will PEGylate your molecule and deliver your PEGylated product with a certificate of analysis, as a regular end-product, for further testing at your site. This is recommended for an initial evaluation of PEGylation approaches.

Service model 2. Complete PEGylation method development service.
Under this service model, JenKem will provide your PEGylated sample, as well as the complete PEGylation method development package, including all developed analytical methods for characterization of your PEGylated product, up to pre-clinical stage. The PEGylation processes developed by JenKem Technology are easily scalable and transferable and consist of the following main steps:

Phase 1: JenKem delivers PEGylated compounds to the customer for pharmaceutical analysis and provides a detailed report including PEGylation reaction conditions, separation and purification processes, and analytical methods for the PEGylated compounds.
PEG reagent screeningPEGylation reaction conditions screeningSeparation and purification process development Analytical method development (HPLC, SDS-PAGE, GPC, and other qualitative or quantitative methods for analysis of PEGylated products) Synthesis, characterization and delivery of PEGylated molecule

Phase 2: JenKem prepares the pre-clinical data of PEGylated compounds and chooses the best PEGylated compounds according to the pharmaceutical data.

Quality specification study of PEGylated moleculesFormulation study of PEGylated molecules
Pharmacodynamics study of PEGylated molecules Toxicology study of PEGylated molecules Please contact our technical support group at [email protected] for more details on our PEGylation services.