Pirfenidone

Potent adrenergic agonist and vasopressor API used to raise vascular tone and blood pressure in acute circulatory failure.

Micronized polyene antifungal API active against Candida and other susceptible yeasts in topical and oral-local formulations.

Steroidogenesis inhibitor API that blocks 11-beta-hydroxylase and is used to control hypercortisolism in Cushing syndrome.

Synthetic anabolic-androgenic steroid API used in selected conditions requiring promotion of weight or lean-tissue gain.

Bisphosphonate API that inhibits osteoclast-mediated bone resorption and is used in hypercalcemia and other high-turnover bone disorders.

Multitargeted antifolate antineoplastic API used in chemotherapy for mesothelioma and selected non-small-cell lung cancers.

CXCR4 antagonist API used to mobilize hematopoietic stem cells into peripheral blood for collection before transplantation.

Antifolate antineoplastic API designed for enhanced cellular uptake and used in selected T-cell lymphomas.

Class IC antiarrhythmic API that blocks cardiac sodium channels and is used for selected atrial and ventricular arrhythmias.

Selective serotonin 5-HT4 receptor agonist API with prokinetic activity used for chronic constipation.

Topical keratolytic and antiseptic active used in dermatological preparations and as a pharmaceutical intermediate.

Nitrogen-containing bisphosphonate API that reduces bone resorption and is used in osteoporosis and related bone disorders.