PIROUETTE 3D Microgravity and extreme biology simulator platform

Traditional laboratory instruments such as clinostats can mimic certain aspects of spaceflight, but cannot fully replicate the conditions. It has been widely acknowledged that many intriguing findings in simulated microgravity result from fluid motions or mechanical stressors. However, there is a significant subset of cellular experiments in simulated microgravity that exhibit similar outcomes to those conducted in space. Exploiting these two worlds leads to a myriad of use cases relevant for terrestrial applications. By precisely manipulating shear forces and mechanical loading and unloading - automated and scalable - researchers can unlock a vast latent space of experimental possibilities. Litegrav’s approach facilitates pathway identification, drug efficacy screening, tailored production of specific cell types with desired traits, and enhanced production of plant and microbial byproducts. Litegrav’s platform bridges the divide between terrestrial labs and the cosmos, offering a powerful tool to advance therapeutics and further our understanding of biology.