ProGsterol

ProGsterol
Product Description

ProGsterol is an oral peptide-based nutraceutical designed to improve insulin receptor sensitivity and regulate glucose metabolism, supporting overall metabolic balance.
Product Overview
ProGsterol is a peptide-based nutraceutical developed by Caregen for metabolic disorders, including insulin resistance, type 2 diabetes, and MASLD. Its active ingredient, Deglusterol, is a proprietary peptide complex derived from Deobetide and Adiporin, designed to improve insulin sensitivity and regulate glucose metabolism. Formulated as a once-daily oral supplement, ProGsterol supports glucose regulation, lipid metabolism, and body composition. In March 2022, Deglusterol completed the U.S. FDA New Dietary Ingredient (NDI) notification, becoming the first synthetic peptide approved under this designation.

Caregen Co.,Ltd.

  • Country/Region:
    Korea, Republic Of
  • Founded:
    2001
  • On CPHI since:
    2016
  • Certificates:
    3
  • Employees:
    100 - 249
Company types
Biopharmaceutical company
Consumer Goods
Distributor/Import Export
Drug delivery device Supplier/Manufacturer
Manufacturer/Innovator
OTC
Other
Primary activities
API Producer
Biopharmaceutical
Cosmeceuticals
Cosmetic Ingredients
Nutraceuticals
OTC
Out-licensing specialist
Pharmaceutical Company (generic finished products)
Pharmaceutical Company (innovator finished products)
Specifications
  • Selling Points
    Human Clinical Results

    Individuals with Metabolic Imbalance- Fasting blood glucose reduction: up to -23 mg/dL
    - Fasting insulin reduction: up to -5.2 μU/mL
    - HOMA-IR reduction: up to -2.3
    - HbA1c reduction: up to -0.9%


    Pre-diabetic Population (12 weeks)
    - Fasting blood glucose: -6.7 mg/dL
    - HbA1c: -0.3%
    - Fasting insulin: -1.03 μU/mL
    - HOMA-IR: -0.43
    - C-peptide: -0.12


    Metabolic Syndrome & Liver Related Conditions
    - Reduction in liver fat grade and overall disease severity over 3 months
    - Improvement in lipid metabolism
    - 56% improvement in NAFLD clinical status after 3 months
    - 21.3% NAFLD cleared after 3 months


    Type 2 Diabetes & MASLD Patients
    - Rapid blood glucose reduction within 30 minutes 
    - HOMA-IR reduction from 3.95 to 1.92 (-2.03) 
    - Enhanced AMPK activation and adiponectin
    - mediated metabolic effect

Caregen Co.,Ltd.

  • Country/Region:
    Korea, Republic Of
  • Founded:
    2001
  • On CPHI since:
    2016
  • Certificates:
    3
  • Employees:
    100 - 249
Company types
Biopharmaceutical company
Consumer Goods
Distributor/Import Export
Drug delivery device Supplier/Manufacturer
Manufacturer/Innovator
OTC
Other
Primary activities
API Producer
Biopharmaceutical
Cosmeceuticals
Cosmetic Ingredients
Nutraceuticals
OTC
Out-licensing specialist
Pharmaceutical Company (generic finished products)
Pharmaceutical Company (innovator finished products)

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