Single B Cell Screening

Biointron offers a high-throughput, fully integrated platform for accelerating antibody discovery. Biointron's high-throughput single B cell screening platform can screen 2*10^6 plasma B-cells from immunized animals. Antigen specific antibody-secreting cells can be isolated. It allows the detection of potentially rare antibodies or drugs with unique properties.

Highlights:

• Microfluidic Technology: Microfluidic-based methods can achieve higher throughput and greater flexibility over nanowell and nanovial techniquesThis technology has been used in research with single-cell genetics, epigenetics, transcriptomics, proteomics and metabolism
• High Efficiency: NGS sequencing & HTP mammalian Production/Validation;
Accelerate therapeutic development for a broad range of targets, including challenging transmembrane proteins
• Short Timeline: Millions of cells can be screened within 1 week. By bypassing conventional hybridoma steps with single B cell screening, you can expect to gain 2-3 months.