Single Domain Antibody Engineering & Functionalization

Single Domain Antibody Engineering & Functionalization
Product Description

We offer advanced downstream protein engineering to equip single-domain antibody candidates with precise structural and functional properties. Leveraging our comprehensive in-house and externally acquired capabilities, we design and produce engineered VHHs featuring bespoke modifications such as multimerization, targeted fusions, and conjugations with near-infrared fluorescent proteins (NIR-FP), luciferase, horseradish peroxidase (HRP), and immunoglobulin G (IgG) Fc domains.

preclinics Italia

  • Country/Region:
    Italy
  • Founded:
    2022
  • On CPHI since:
    2026
  • Employees:
    1 - 24
Company types
Start-up
Primary activities
Contract Research Organisation

preclinics Italia

  • Country/Region:
    Italy
  • Founded:
    2022
  • On CPHI since:
    2026
  • Employees:
    1 - 24
Company types
Start-up
Primary activities
Contract Research Organisation

More Products from preclinics Italia (3)

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    Product Antigen Engineering & Production

    We custom-express and purify proteins for use as immunogenic antigens. Our team actively engineers and optimizes difficult proteins to maximize both immunogenicity and stability, ensuring the highest quality starting material for your discovery campaigns.
  • Custom Single Domain Antibody Discovery & Screening

    Product Custom Single Domain Antibody Discovery & Screening

    We provide end-to-end single-domain antibody discovery using bespoke camelid immunization and advanced phage display strategies. We design tailored screening conditions to isolate rare, functional binders with specific properties, such as pH dependence or cross-species reactivity.
  • Protein Expression & Purification

    Product Protein Expression & Purification

    We offer production of single-domain antibodies and a wide range of other recombinant proteins utilizing adaptable microbial expression systems like E. coli and Pichia pastoris. By pairing these versatile expression platforms with optimized purification conditions, we deliver high-quality molecules at scal...