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Succinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate (SMCC)

Succinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate (SMCC)
Product Description

Succinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate (SMCC) is a high-purity, bifunctional crosslinker widely used in the synthesis of antibody-drug conjugates (ADCs). It contains an NHS ester group that reacts with primary amines and a maleimide group that selectively binds to thiol groups. The cyclohexane backbone enhances structural rigidity and stability, making it ideal for forming durable covalent bonds in bioconjugation processes.

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DAPIN GmbH

  • Country/Region:
    Germany
  • On CPHI since:
    2025
  • Certificates:
    1
  • Employees:
    50 - 99
Company types
CMO/CDMO
Primary activities
API Producer
Chemical Development
View company profile
Categories
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Specifications
  • CAS Registry Number
    64987-85-5
  • Details
    - Antibody-Drug Conjugates (ADCs): Enables precise linkage of cytotoxic payloads to monoclonal antibodies, improving targeted cancer therapy by minimizing off-target toxicity.- Protein Labeling: Facilitates the attachment of fluorescent dyes, enzymes, or other tags to proteins for analytical and imaging purposes.
    - Bioconjugation: Used to couple biomolecules such as peptides, oligonucleotides, or enzymes in research and diagnostics.
    - Drug Delivery Systems: Its stable structure supports the development of robust delivery platforms under physiological conditions.
  • Supplied from
    Germany
More specifications Fewer specifications

DAPIN GmbH

  • Country/Region:
    Germany
  • On CPHI since:
    2025
  • Certificates:
    1
  • Employees:
    50 - 99
Company types
CMO/CDMO
Primary activities
API Producer
Chemical Development
View company profile

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