Tafamidis

Tafamidis
Product Description

Tafamidis API – Stabilizing Transthyretin for Amyloidosis Management

Tafamidis is a high-purity Active Pharmaceutical Ingredient (API) developed by Chemex Global, designed for the treatment of transthyretin-mediated amyloidosis (ATTR). It functions as a selective stabilizer of the transthyretin (TTR) protein, preventing its misfolding and subsequent amyloid fibril formation. This mechanism is crucial in managing both hereditary and wild-type forms of ATTR, which can lead to cardiomyopathy and peripheral neuropathy.

At Chemex Global, Tafamidis is synthesized under stringent quality standards, ensuring optimal purity and efficacy. The API is available in its free acid form, enhancing its solubility and bioavailability for pharmaceutical formulations. Our commitment to excellence ensures that Tafamidis meets the rigorous demands of global healthcare providers seeking effective solutions for rare and life-threatening conditions.

Read more Show less

Chemex Global

  • Country/Region:
    India
  • Founded:
    2021
  • On CPHI since:
    2024
  • Certificates:
    2
  • Employees:
    50 - 99
Company types
Pharmaceutical company
Primary activities
API Producer
View company profile
Categories
more categories Show less
Specifications
  • CAS Registry Number
    594839-88-0
  • Details
    Tafamidis is a high-purity Active Pharmaceutical Ingredient (API) developed by Chemex Global, designed for the treatment of transthyretin-mediated amyloidosis (ATTR). It functions as a selective stabilizer of the transthyretin (TTR) protein, preventing its misfolding and subsequent amyloid fibril formation. This mechanism is crucial in managing both hereditary and wild-type forms of ATTR, which can lead to cardiomyopathy and peripheral neuropathy.
  • Selling Points
    Prompt Delivery; Quality Service; Dual Polymorphic Forms, High Purity, Regulatory Compliance, Suitable for Oral Solid Formulation, Innovative Therapeutic Solution, Global Market Access, Manufacturing Excellence, Manufacturing Excellence
  • Supplied from
    India
  • Measured In
    gram; kilogram; milligram
More specifications Fewer specifications
Sales Markets
Show more Show less

Chemex Global

  • Country/Region:
    India
  • Founded:
    2021
  • On CPHI since:
    2024
  • Certificates:
    2
  • Employees:
    50 - 99
Company types
Pharmaceutical company
Primary activities
API Producer
View company profile

More Products from Chemex Global (12)

  • Sitagliptin Phosphate Monohydrate

    Product Sitagliptin Phosphate Monohydrate

    Sitagliptin phosphate is a trusted, effective solution for managing Type 2 Diabetes. As a leading DPP-4 inhibitor, it helps patients achieve better blood sugar control by naturally boosting insulin levels and reducing glucagon, without causing weight gain or low blood sugar episodes. Manufactured to th...
  • Dapagliflozin Propanediol

    Product Dapagliflozin Propanediol

    Dapagliflozin Propanediol Monohydrate (CAS No. 960404-48-2) is a high-purity Active Pharmaceutical Ingredient (API) used in the management of Type 2 Diabetes Mellitus. As a selective Sodium-Glucose Co-Transporter 2 (SGLT2) inhibitor, it lowers blood glucose levels by preventing glucose reabsorption in ...
  • Sacubitril Sodium

    Product Sacubitril Sodium

    Sacubitril Sodium is a high-purity Active Pharmaceutical Ingredient (API) used in the treatment of chronic heart failure with reduced ejection fraction (HFrEF). As a potent neprilysin inhibitor, it enhances the effects of natriuretic peptides, leading to vasodilation, natriuresis, and diuresis. When co...
  • Sacubitril - Valsartan Complex

    Product Sacubitril - Valsartan Complex

    Sacubitril-Valsartan Complex is a high-purity Active Pharmaceutical Ingredient (API) combining sacubitril, a neprilysin inhibitor, and valsartan, an angiotensin II receptor blocker (ARB). This synergistic formulation is designed to treat chronic heart failure with reduced ejection fraction (HFrEF), eff...
  • Midodrine

    Product Midodrine

    Midodrine is a synthetic vasopressor agent and prodrug that is metabolized in the body to its active form, desglymidodrine, a selective α1-adrenergic receptor agonist. It is commonly used in the treatment of symptomatic orthostatic hypotension by increasing vascular tone and blood pressure. The compoun...
  • Midodrine Hydrochloride

    Product Midodrine Hydrochloride

    Midodrine Hydrochloride is a high-purity Active Pharmaceutical Ingredient (API) designed for the treatment of symptomatic orthostatic hypotension. As a selective α₁-adrenergic receptor agonist, it induces vasoconstriction, thereby elevating blood pressure in patients experiencing significant drops upon...
  • Vildagliptin

    Product Vildagliptin

    Unlock the power of precision in diabetes care with Vildagliptin, a trusted DPP-4 inhibitor API designed for today’s Type 2 Diabetes management. Engineered to the highest IP standards, Vildagliptin delivers proven efficacy by enhancing incretin levels, improving insulin response, and reducing glucagon ...
  • (3R,4S,5R,6R)-3,4,5-tris(trimethylsilyloxy)-6-((trimethylsilyloxy)methyl)-tetrahydropyran-2-one

    Product (3R,4S,5R,6R)-3,4,5-tris(trimethylsilyloxy)-6-((trimethylsilyloxy)methyl)-tetrahydropyran-2-one

    (3R,4S,5R,6R)-3,4,5-Tris(trimethylsilyloxy)-6-((trimethylsilyloxy)methyl)tetrahydropyran-2-one (CAS No. 32384-65-9) is a high-purity pharmaceutical intermediate (≥95%) crucial in synthesizing SGLT2 inhibitors like Dapagliflozin, Empagliflozin, and Canagliflozin for type 2 diabetes treatment. This moistu...
  • (5-bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone

    Product (5-bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone

    (5-Bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone (CAS No. 461432-22-4) is a white to off-white crystalline compound with the molecular formula C15H12BrClO2 and a molecular weight of 339.61 g/mol. It features a substituted benzophenone structure and is primarily used as an intermediate in pharmaceutica...
  • 1-(2,5-Dimethylphenyl)-2-aminoethanol Hydrochloride

    Product 1-(2,5-Dimethylphenyl)-2-aminoethanol Hydrochloride

    1-(2,5-Dimethylphenyl)-2-aminoethanol hydrochloride is a high-purity pharmaceutical intermediate with the molecular formula C₁₀H₁₆ClNO and a molecular weight of 201.7 g/mol. It appears as a white to off-white crystalline powder and is soluble in water and ethanol. This compound serves as a crucial build...
  • 2-(4-ethoxybenzyl)-4-bromo-1-chlorobenzene

    Product 2-(4-ethoxybenzyl)-4-bromo-1-chlorobenzene

    2-(4-Ethoxybenzyl)-4-bromo-1-chlorobenzene (CAS No. 461432-23-5) is a high-purity pharmaceutical intermediate essential in the synthesis of Dapagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor used for managing type 2 diabetes mellitus. This compound, also known as 4-bromo-1-chloro-2-(4-e...
  • Contract Development and Manufacturing Organization

    Product Contract Development and Manufacturing Organization

    Chemex Global provides comprehensive Contract Development and Manufacturing Organization (CDMO) services specializing in small molecule Active Pharmaceutical Ingredients (APIs). Our services cover the entire product lifecycle—from early-stage process development and route optimization to scale-up, commerci...

Chemex Global resources (1)

  • Inside Chemex Global: API/Pharma Intermediates manufacturing facility and R&D Lab

    Video Inside Chemex Global: API/Pharma Intermediates manufacturing facility and R&D Lab

    Welcome to Chemex Global in Guwahati, Assam—a leading manufacturer of Active Pharmaceutical Ingredients (APIs). Our advanced facility, one of Eastern India’s largest R&D labs, is home to dedicated scientists developing cutting-edge APIs and pharmaceutical intermediates. We ensure top quality through rigorous QA and QC, adhering to GMP and GDP standards for purity, potency, and safety. Committed to environmental responsibility, we use innovative technologies to minimize our ecological impact.
    2025-06-02