In accordance with
GMP, Appendix 1, when filling vials with pharmaceutical products, the stopper gap
must be checked using a suitable inspection system before the crimped cap is
fitted in order to minimize microbiological contamination.
Machine Vision is the best technology to perform these inspections and measure the
gap width between the bottom edge of the stopper and the top of the vial. Normally a gap of 1 mm is allowed, measured at
conveying speeds of 40 m/min.
The Octum image processing system for stopper gap inspection meets all customer
requirements. The stopper gap is measured at four locations with an accuracy of
±0.05 mm or better. The cameras are housed in an insulator-capable stainless
steel housing together with the LED lighting. This space-saving layout permits
the system to be ideally integrated into the filling line for both use cases
with vials in the linear conveying direction as well as to circular path
movement in the transport star.
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