2
Jun
2026

NOF CORPORATION

Exhibitor at CPHI Americas 2026 stand 623
About Us

NOF CORPORATION is the leading commercial supplier of GMP grade activated PEGs, lipids and ultrapure Polysorbates 80 for drug delivery products through R&D to commercial scale. We provide a wide range of lipids (ionizable, PEG, and phospho) for lipid nanoparticle formulations (LNP). Our LNP platform, containing our ionizable lipid (COATSOME® SS Series), has excellent endosomal escape ability and provides high gene expression with low toxicity. It is capable of applying to gene delivery, gene editing, and RNA vaccine application under this platform.

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  • Country/Region:
    United States
  • On CPHI since:
    2018
  • Employees:
    1000 - 4999
Company types
Drug delivery device Supplier/Manufacturer
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Event information
CPHI Americas 2026
  • 2 Jun 2026 - 4 June 2026
  • Pennsylvania Convention Center, Philadelphia
  • Visit us at stand 623

Products Featured at CPHI Americas 2026

  • Acetal-Linkage Releasable PEGs

    Product Acetal-Linkage Releasable PEGs

    NOF has developed releasable PEG derivatives that have cleavable acetal linkers in physiological environment(pH7.4). The PEGylated drug by releasable PEGs release native drug through hydrolysis and 1,4-elimination.The release rate of bioactive substance can be controlled with linker structures.
  • Activated PEG-Lipids for Targeting Lipid Nanoparticles

    Product Activated PEG-Lipids for Targeting Lipid Nanoparticles

    For specific delivery, nanoparticles modified with ligands are widely used.Conventional modifying agents, such as activated PEG-phospholipids, have an ioniccharge.It is complicated to apply them to lipid nanoparticles (LNP), as they have anegative impact on a charge and stability of LNP.NOF newly developed...
  • COATSOME SS Series_Novel Lipid Nanoparticle Platform

    Product COATSOME SS Series_Novel Lipid Nanoparticle Platform

    We have newly developed COATSOME® SS Series foreffective intracellular delivery and lower toxicity.COATSOME® SS Series contains dual sensing motifs thatcan respond to the intracellular environment; tertiaryamines respond to an acidic compartment (endosome/lysosome) for membrane destabilization, and disulfi...
  • Custom Lipid Synthesis for Pharmaceutical Applications

    Product Custom Lipid Synthesis for Pharmaceutical Applications

    NOF CORPORATION has manufactured and supplied high purity GMP-grade phospholipids and other lipid derivatives to pharmaceutical companies worldwide since the early 1990s. These are suitable for lipid emulsion, liposome,and lipid nanoparticle (LNP / targeted LNP)formulations.
  • High purity PEG Diacylglycerols for Lipid Nanoparticles

    Product High purity PEG Diacylglycerols for Lipid Nanoparticles

    NOF has succeeded in developing PEG lipids (diacylglycerol-type PEG lipids with various PEG molecular weights and acyl chain lengths for lipid nanoparticle (LNP)applications) with higher purity and extremely low levels of impurities compared to PEG lipids available from other companies. Leveraging our year...

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