NOF CORPORATION
About NOF CORPORATION
Categories
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Country/Region:United States
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On CPHI since:2018
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Employees:1000 - 4999
Company types
Products from NOF CORPORATION (3)
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Product Acetal-Linkage Releasable PEGs
NOF has developed releasable PEG derivatives that have cleavable acetal linkers in physiological environment(pH7.4). The PEGylated drug by releasable PEGs release native drug through hydrolysis and 1,4-elimination.The release rate of bioactive substance can be controlled with linker structures. -
Product Activated PEG-Lipids for Targeting Lipid Nanoparticles
For specific delivery, nanoparticles modified with ligands are widely used.Conventional modifying agents, such as activated PEG-phospholipids, have an ioniccharge.It is complicated to apply them to lipid nanoparticles (LNP), as they have anegative impact on a charge and stability of LNP.NOF newly developed... -
Product COATSOME SS Series_Novel Lipid Nanoparticle Platform
We have newly developed COATSOME® SS Series foreffective intracellular delivery and lower toxicity.COATSOME® SS Series contains dual sensing motifs thatcan respond to the intracellular environment; tertiaryamines respond to an acidic compartment (endosome/lysosome) for membrane destabilization, and disulfi...
