ABResearch srl

About ABResearch srl

Founded in 2009 by professionals with a strong experience in Nutraceuticals and Nutricosmetics, ABR represents the junction between the innovation offered by biotechonology and classic production methods of actives. As matter of fact, ABR developed a proprietary industrial platform for the production of active ingredients extracted from specifc, non GMO, natural plant cells. A long story of pioneering collaborations with top international research centres and accredited laboratories is the basis of ABR success, committed to the production of unique products devoted to human health with particular care to preserve the nature and the environment. 
We are inspired by nature and entrust biotechnology to uncover the magic of botanical ingredients to support human health. We are a green mindset company that ideated new sustainable industrial processes to get the most out of smart plant cell cultures, respecting and preserving the environment.
A cutting-edge technology designed for the production of highly pure and active novel ingredients. Natural plant cell culture is the election technology to extract organic molecules with  standardized profiles in a fully controlled environment where the advantages become a must:  
• No impoverishment of the soil and forests;
• Reduction in the use of hydric resources;
• Unlimited availability of ingredients
• No influence on seasonality;
• Free from pollutants, fertilizers, pesticides and aflatoxins.

Certifications
  • IT
  • 2020
    On CPhI since
  • 3
    Certificates
  • 25 - 49
    Employees
Contract Service
Manufacturer/Innovator
Contact info

Products from ABResearch srl

  • ACTEOS 10P - Lippia citriodora cell culture extract

    Product ACTEOS 10P - Lippia citriodora cell culture extract

    Lippia Citriodora cell culture extract.Verbascoside (VB), also named Acteoside, is a phenylpropanoid glycosides water-soluble classified.
    The plant extracts, titled in VB, possesses broad-spectrum anti-inflammatory, anti-hypertensive, anti-asthmatic, anti-oxidative and immunotoxin properties. VB downregulates expression and activity of NOS and COX-2 enzymes and inhibits the activation of TAK-1/JNK/AP-1 signaling pathway by tyrosine phosphatase SHP-1 activation. Several studies have also shown that VB inhibits also NFкB pathways and the downstream expression of primary pro-inflammatory cytokines, such as IL-1, IL-6 and TNF-α. Our internal study shows p62 upregulation in autophagy induction, suggesting an important anti-aging activity.

    Recently, VB has shown a potent antiviral effect against Respiratory Syncytial Virus RSV, Herpes Simplex Virus HSV-1 and HSV-2.
  • APPLIVER® CHOLESTEROL

    Product APPLIVER® CHOLESTEROL

    APPLIVER® CHOLESTEROL is the new product obtained by the ABR innovative biotechnological platform NATRISE®.
    APPLIVER® is a freeze-drying  Cydonia oblonga stem cells compound obtained by plant cell culture.
    The Cydonia oblonga is anapple-shaped fruit, with a delicious aroma and it is known for its exceptional health activities sinceancient times.

    APPLIVER® is administered, a significant reduction of total cholesterol and VLDL/LDL-cholesterol level was observed. The HDL-cholesterol level (the “good cholesterol transport”) was higher compared to the control. Indeed, it acts as scavenger of cholesterol excess.
  • APPLIVER® FIBROSIS

    Product APPLIVER® FIBROSIS

    APPLIVER® is the new product obtained by the ABR innovative biotechnological platform NATRISE®.
    APPLIVER® is a freeze-drying Cydonia oblonga  fruit stem cells culture. The  Cydonia oblongais an apple-shaped fruit, with a delicious aroma and it is known for its exceptional health activities since ancient times.
    APPLIVER® treatment shows a significant decrease of the cytokines production as TNF-α both in serum and in liver tissue.
    The prominent production of fibrillar type 1 collagen is associated with extracellular matrix remodelling and liver fibrosis.  When APPLIVER® is administered, the production of the collagen was decreased both on gene and protein level.
  • APPLIVER® GLYCAEMIA

    Product APPLIVER® GLYCAEMIA

    APPLIVER® is the new product obtained by the ABR innovative biotechnological platform NATRISE®.
    APPLIVER® is a freeze-drying  Cydonia oblonga stem cells compound obtained by fruit cell culture.In comparison with fruit, our cell culture present 50% glucidic less.
    Hyperglycaemia affects people who have diabetes, because they have too little insulin or can't use insulin properly.
    In our studies, the Oral Glucose Tolerance Test was performed and when APPLIVER® was administered, we observed a decrease of the glucose level. These findings are APPLIVER® dose-depending.
  • APPLIVER® STEATOSIS

    Product APPLIVER® STEATOSIS

    APPLIVER® STEATOSIS is the new product obtained by the ABR innovative biotechnological platform NATRISE®.
    APPLIVER® is a freeze-drying  Cydonia oblonga stem cells obtained by plant cell culture.

    APPLIVER® treatment shows a significant decrease of the cytokines production as TNF-α both in serum and in liver tissue. The liver weight and the visceral fat were significantly reduced when APPLIVER® was administered, and there’s a dose dependent relationship that confirms its beneficial effect.
  • EchiPLUS - Echinacea angustifolia cell culture extract

    Product EchiPLUS - Echinacea angustifolia cell culture extract

    ECHINACOSIDE+DCQ+AC. CLOROGENIC
    Biological effects
    ABR conducted in vitro and in vivo studies that demonstrated ECHIPLUS antioxidative properties. Specifically, ABR is proprietary of a clinical trial on sport practitioners where the protective action of ECHIPLUS  is evident against lipoperoxidation related damages.

    Other clinical studies, in literature, showed also Echinacoside beneficial effects in:
    • Fighting flu and flu-like infections;
    • Immunosuppressive conditions;
    • Reducing risk of medical complications in upper respiratory tract infections;
    • Modulating EPO production without affecting red blood cells count.
  • Teupol10P Teupol25P Teupol40P - Ajuga reptans cell culture extract

    Product Teupol10P Teupol25P Teupol40P - Ajuga reptans cell culture extract

    TEUPOLIOSIDE - Biological effects
    ABR conducted in vitro and in vivo studies that demonstrated Teupolioside antinflammatory and antioxidative properties. Teupolioside was proved to be effective in:
    • Benign prostatic hyperplasia (BPH);
    Crohn’s syndrome and gastro-intestinal chronic diseases

    Teupolioside is a secondary metabolite produced by the plant with defensive aim against environmental agents such as UV radiations. Its scarce quantity in the whole plant is the reason for which this ingredient can be hardly secured with classical extraction methods .

ABResearch srl Resources

  • Brochure APPLIVER FIBROSIS

    APPLIVER® is the new product obtained by the ABR innovative biotechnological platform NATRISE®.
     Our research studies confirm the beneficial effect on health of APPLIVER® in metabolic disorder as NAFLD.

    This makes APPLIVER® the perfect ingredient for dietary supplements and functional foods.
  • Brochure NATRISE PROFECUNDO

    ProFecundo is the new product obtained by the ABR innovative biotechnological platform NATRISE®.
    IT IS A MIXTURE OF NATURAL EXTRACTS FROM PLANT STEM CELL CULTURE RICH IN POLYPHENOL.

    ProFecundo showed a significant improvement on sperm quality.
  • Brochure APPLIVER CHOLESTEROL

    APPLIVER® is the new product obtained by the ABR innovative biotechnological platform NATRISE®.
    Our research studies confirm the beneficial effect on health of APPLIVER® in metabolic disorder as dyslipidaemia.

    This makes APPLIVER® the perfect ingredient for dietary supplements and functional foods.
  • Brochure APPLIVER GLYCAEMIA

    APPLIVER® is the new product obtained by the ABR innovative biotechnological platform NATRISE®.
    Our research studies confirm the beneficial effect on health of APPLIVER® in metabolic disorder as hyperglycaemia.

    This makes APPLIVER® the perfect ingredient for dietary supplements and functional foods.
  • Brochure APPLIVER STEATOSIS

    APPLIVER® is the new product obtained by the ABR innovative biotechnological platform NATRISE®.
    Our research studies confirm the beneficial effect on health of APPLIVER® in steatohepatitis.

    This makes APPLIVER® the perfect ingredient for dietary supplements and functional foods.
  • Brochure Company Profile ABResearch Srl

    Our company profile with your Novel Food products and our services: our innovative technology for the development of plant cell lines of your interest.
  • Brochure Ajuga reptans - cell culture extract

    Ajuga reptans, is part of the Lamiaceae family, present in the temperate regions in the grassy areas of Europe, western Asia and North Africa.Ajuga reptans has been used since the Middle Ages as a healing agent and to treat ulcerations but also for its anti-haemorrhagic and anti-inflammatory properties.Our comparative studies demonstrate activity on benign prostatic hypertrophy and ulcerative colitis.
  • Brochure ACTEOS - Lippia citriodora cell culture extract

    Lippia citriodora, commonly known as Lemon Verbena or Lemon beebrush, is synonymous with Aloysia triphylla, Verbena citriodora and Verbena triphyilla. Plants of genus Lippia were and are still generally used by indigenous populations of South America and by the traditional Chinese medicine for respiratory diseases such as cold and fl u, cough and bronchitis.


    Additionally, Lippia citriodora leaves are used as seasoning for food preparations or flavoring for beverages.


    Lippia is used in medicine as a relaxant and carminative herb that counteracts stress related conditions, especially those that affect the stomach.
    Other medical uses regard the treatment of dyspepsia, headaches, neuralgic pain and vertigo. 
  • Brochure Rosmarinic Acid from plant cell culture

    Meristematic cells, or plant stem cells, are totipotent undifferentiated cells from which all plant tissues originate.
    ABResearch platform offers a new perspective on the use of Ocimum basilicum from stem cell cultures to obtain Rosmarinic Acid without aroma.
  • Technical Data Clinical evaluation on sporty people

    Assessment of oxidative status in athletes treated with EchiPLUS
  • Technical Data Glabridine

    Glabridin, a prenylated isoflavonoid of G. glabra L. roots (European licorice, Fabaceae), has been associated with a wide range of biological properties such as antioxidant, antiinflammatory, anti-atherogenic, regulation of energy metabolism, estrogenic, neuroprotective, anti-osteoporotic, skin-whitening
  • Whitepaper NatRise philosophy - scale-up plant cell culture using ABResearch biotechnology

    ABResearch srl has developed on industrial scale Plant Cell Culture biotechnological platform to produce and extract secondary metabolites to nutraceutical and cosmetics use. This innovative approach has numerous advantages over conventional methods as the traditional production of crops. In fact, plant cell cultures ensure a high degree of quality and safety and serve to improve reproducibility and standardization in the composition of the final product. Furthermore, the technique is totally environmentally-friendly since no other plant tissue is required, and it obviates geographical, climatic, and seasonal variations which plague traditional plant harvesting. Thus, this approach provides a programmable and flexible production process.

  • Video ABResearch - industrial scale of plant cell culture

    ABResearch innovative technological platform for the industrial-scale growth of secondary metabolites from plant cell culture.