Deucravacitinib

Intermediate and metabolite of the gastrokinetic and antinauseant drug Domperidone.

An antibiotic that blocks synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase

Tamoxifen is a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Tamoxifen is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast cancer, the gene repressor ...

A metal-complexing agent; an effective iron chelating agent to help protect against UVB radiation. An impurity of Chlorpheniramine Maleate . ;Impurity in commercial preparations of Chlorpheniramine.

Tert-Butanol-d₉ ((CD₃)₃COD) is a high-purity deuterated solvent and versatile isotope-labeled building block used in the synthesis of stable isotope-labeled pharmaceuticals, intermediates, and analytical reference standards. It enables the efficient incorporation of deuterated tert-butyl groups into target...

Bromocyclopentane-d₉ is a high-purity deuterated alkyl bromide widely used as a versatile building block in the synthesis of stable isotope-labeled pharmaceuticals, intermediates, and analytical reference standards. It enables the efficient introduction of a deuterated cyclopentyl group into complex organi...

Deutetrabenazine is a first-in-class, orally bioavailable deuterated vesicular monoamine transporter 2 (VMAT2) inhibitor approved for the treatment of chorea associated with Huntington’s disease and tardive dyskinesia. 

Deutivacaftor  is an orally active, deuterated cystic fibrosis transmembrane conductance regulator (CFTR) potentiator designed to improve salt and water transport across cell membranes. As a deuterium-substituted analogue of ivacaftor, it utilizes targeted carbon-deuterium bonds to resist CYP3A-mediat...

Methylboronic Acid-d₃ (CD₃B(OH)₂) is a high-purity deuterated organoboron building block widely used in the synthesis of stable isotope-labeled pharmaceuticals, advanced intermediates, and analytical reference standards. It is an essential reagent for Suzuki–Miyaura cross-coupling reactions, enabling the e...

Methyl iodide-d₃ (CD₃I) is a high-purity deuterated methylating reagent widely used in the synthesis of stable isotope-labeled pharmaceuticals, intermediates, metabolites, and analytical reference standards. It enables the efficient incorporation of a deuterated methyl (–CD₃) group into complex organic mol...

Methyl Tosylate-d₃ (CD₃OTs) is a high-purity deuterated methylating reagent widely used in the synthesis of stable isotope-labeled pharmaceuticals, intermediates, and analytical reference standards. It enables the efficient introduction of a deuterated methyl (–CD₃) group into target molecules, making it a...

Methylamine-d₃ Hydrochloride serves as a key deuterated building block for introducing a CD₃-labeled methylamine moiety into complex organic molecules. It is extensively used in the preparation of deuterated drug candidates, impurities, and metabolites, including compounds such as: Deucravacitinib-d₃ ...

Clearsynth Labs Limited is a technology-based, research-driven, innovation-led enterprise specializing in deuterium chemistry and stable isotopes. Headquartered in Mumbai, with an R&D center in Hyderabad and a CDMO facility in Karnataka, alongside operations in Canada and the USA, we deliver solutions from milligram-scale R&D to multi-ton manufacturing. Our expertise spans deuterated APIs, intermediates, impurities, and reference standards. Backed by strong IP and 350+ scientists, we partner with innovators and generics across CDMO and CMO segments, committed to precision, quality, and advancing next-generation isotopic solutions for global pharmaceutical needs.