Lisdexamfetamine Dimesylate

Elacestrant Dihydrochloride is a high-purity Active Pharmaceutical Ingredient (API) and oral Selective Estrogen Receptor Degrader (SERD). It selectively targets and degrades estrogen receptor-alpha ($\text{ER}\alpha$), offering a targeted oncological treatment for postmenopausal women and adult men with&nb...

High-purity Elacestrant Impurity 3   is a key chemical intermediate and structural analogue involved in the synthesis of Elacestrant. It serves as a vital building block for active pharmaceutical ingredient (API) manufacturing and as an analytical reference standard for impurity profiling, method...

N-Ethyl-2-(4-formylphenyl)acetamide is an essential organic intermediate and structural fragment used in the multi-step chemical synthesis of Elacestrant. It acts as a key building block during late-stage coupling reactions and serves as a vital analytical reference standard for impurity profiling, method ...

Ruxolitinib is an orally active, potent, and selective Janus kinase (JAK1 and JAK2) inhibitor. It is indicated for the treatment of myelofibrosis, polycythemia vera, graft-versus-host disease (GvHD), and atopic dermatitis/vitiligo (topical formulation). Manufactured under strict GMP guidelines for use in p...

2-(3,4-bis(methoxy-d3)phenyl)ethan-1-amine is an advanced deuterated intermediate essential for the commercial synthesis and manufacturing of Deutetrabenazine (API)

Acetone-d₆ is a versatile deuterated reagent and solvent designed for stable isotope labeling applications. It is extensively used in the synthesis of deuterated APIs, intermediates, metabolites, and analytical reference standards. Its high isotopic purity ensures reliable deuterium incorporation, making i...

Tert-Butanol-d₉ ((CD₃)₃COD) is a high-purity deuterated solvent and versatile isotope-labeled building block used in the synthesis of stable isotope-labeled pharmaceuticals, intermediates, and analytical reference standards. It enables the efficient incorporation of deuterated tert-butyl groups into target...

Deucravacitinib is a first-in-class, oral, allosteric tyrosine kinase 2 (TYK2) inhibitor that selectively targets the enzyme's regulatory domain to suppress inflammatory cytokine pathways (IL-23, IL-12, Type I IFNs) while sparing JAK1–3. Approved for the treatment of moderate-to-severe plaque psoriasis, it...

Tert-Butanol-d₁₀ ((CD₃)₃COD) is a high-purity deuterated alcohol widely used as a solvent and isotope-labeled building block for the synthesis of stable isotope-labeled pharmaceuticals, intermediates, and analytical reference standards. It provides an efficient source of deuterium for the preparation of de...

Deutivacaftor  is an orally active, deuterated cystic fibrosis transmembrane conductance regulator (CFTR) potentiator designed to improve salt and water transport across cell membranes. As a deuterium-substituted analogue of ivacaftor, it utilizes targeted carbon-deuterium bonds to resist CYP3A-mediat...

Specialised in Deuterium Chemistry, Clearsynth Manufactures Deuterated Reagents, Deuterated Intermediates and Deuterated APIs (such as Deutetrabenazine, Deuruxolitinib, Deutivacaftor, Deucravacitinib, Donafenib)

Production capacity from mg to tons scale.

Our key reagents are Benzene D...

Clearsynth is a globally trusted partner for reference standards and research chemicals. We offer over 3,000 nitrosamine impurities, 5,000+ stable isotopes, and 10,000+ drug impurities, encompassing a vast portfolio of more than 325,000 products serving various industries, including pharmaceuticals, clinic...

Clearsynth Labs Limited is a technology-based, research-driven, innovation-led enterprise specializing in deuterium chemistry and stable isotopes. Headquartered in Mumbai, with an R&D center in Hyderabad and a CDMO facility in Karnataka, alongside operations in Canada and the USA, we deliver solutions from milligram-scale R&D to multi-ton manufacturing. Our expertise spans deuterated APIs, intermediates, impurities, and reference standards. Backed by strong IP and 350+ scientists, we partner with innovators and generics across CDMO and CMO segments, committed to precision, quality, and advancing next-generation isotopic solutions for global pharmaceutical needs.