Aralez Bio

About Aralez Bio

Aralez Bio is the emerging leader in enzymatic synthesis of novel aromatic amino acids. Our noncanonical amino acids (ncAAs) can be made with unprecedented chemical diversity allowing pinpoint placement of functional groups around an aromatic ring. Our platform is based on traditional biotechnology resulting in ncAAs that are lower in cost, delivered with reliable lead times, and supplied at both small and large-scale batch sizes. Applications for our aromatic chiral building blocks span across industries - therapeutics, diagnostics, and cosmeceuticals.

  • US
  • 2021
    On CPHI since
  • 1
    Certificates
  • 1 - 24
    Employees
Company types
Manufacturer/Innovator
Primary activities
Intermediates Manufacturer
Contact info
  • 1933 Davis Street, San Leandro, CA, United States
Meet us at

CPHI North America 2024

Pennsylvania Convention Center, Philadelphia
07 May 2024 - 09 May 2024

Products from Aralez Bio (5)

  • Other Aromatic Analogs and Derivatives

    Product Other Aromatic Analogs and Derivatives

    Our enzyme platform creates combinatorial diversity by allowing other aromatic subtrates to act nucleophiles and form other aromatic amino acid analogs.
  • D-amino acids

    Product D-amino acids

    As peptide therapeutics experience explosive growth, the need to address the pharmacokinetic liabilities of canonical L-amino acids grows. D-amino acids are less susceptible to enzymatic degradation and, when placed appropriately in a peptide or protein sequence, can confer additional selectivity and potency.
  • N-methylated amino acid analogs

    Product N-methylated amino acid analogs

    N-methylation (and N-alkylation more broadly) increases steric hindrance around the peptide bond, reducing the peptide’s entropy and increasing affinity and selectivity. This modification also confers protease resistance, and the disruption of hydrogen bonds can improve bioavailability.
    Access to N-me...
  • Quaternary Chiral Center Amino Acids

    Product Quaternary Chiral Center Amino Acids

    Previously hard to access, these compounds with all carbon chiral centers are more stable than tertiary chiral centers. Without using enzymes, these structures are very difficult to make using traditional/conventional chemistry.