Research & Development News
Research & Development news
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News Using mobile phones to fight Alzheimer’s disease
Researchers study how radiofrequency electromagnetic fields could be used in Alzheimer’s disease therapy. -
News Researchers develop 3D printed ingestible pill
Represents the first non-invasive diagnostic tool capable of providing a profile of microbiome populations throughout the entire GI tract. -
News Needle free: Erase wrinkles without injection
Meet REVOLUTION BEYOND INNOVATION at Cphi Worldwide 2019, Booth No. 42C06 -
News Eisai collaborates with University of Dundee on cancer drug discovery
It is hoped that research into PROTACs will lead to new drug discoveries for proteins present in cancer, which are difficult to treat with conventional small molecule inhibitors. -
News Fresh data on protein interactions in Alzheimer’s disease
Demonstrates the unique ability of diffusional sizing to assess protein binding in-solution and for difficult-to-study systems. -
News Cyclolab Ltd strengthens its position in the market
Cyclolab Ltd. is an R&D and cGMP manufacturing company focusing on all aspects of cyclodextrin science, manufacturing and applications for cyclodextrin, Dexolve, Sugammadex, formulation development, custom synthesis, Niemann Pick C. -
News Inaugural Bio Integrates conference highlights industry's inefficiency in developing products
Industry leaders give voice to issues and trends shaping the biotech sector, including the importance of collaboration. -
News Clinical supply milestone reached for triple-negative breast cancer treatment
PhoenixMD and WuXi STA have produced a multikilogram drug supply for PMD-026 under GMP manufacturing practices. -
News Trial finds vitamin D does not prevent type 2 diabetes in people at high risk
No meaningful difference between the two study groups regardless of age, sex, race or ethnicity. -
News Partnership seeks breath biomarkers for the early detection of malignant mesothelioma
Owlstone Medical and IAHFIAW to use Breath Biopsy to examine the chemicals found on the breath of individuals with documented historical exposure to asbestos and radiologically and histologically confirmed mesothelioma. -
News Lilly gets its hands on non-opioid pain asset
Early-phase molecule from Centrexion to be developed further as a potential non-opioid treatment option for multiple pain conditions. -
News Updated clinical trial simulation software saves time and money
One customer saves $25m and 3 years' development time in their clinical development strategy. -
News Merck bolsters oncology pipeline with acquisition
Acquisition includes novel late-stage renal cell carcinoma candidate, PT2977. -
News Follicum files patent application for new topical formulation for hair loss
Using easy-to-apply cream instead of direct scalp injection would extend patent protection by 8 years. -
News Hovione Technology acquires global rights to new pulmonary inhaler device
The Papillon DPI is a single-part, blister-based, reusable inhaler, suitable for both chronic and acute treatments. -
News Isotype-specific secondary antibodies for improved signal detection
Offers an alternative to cross-adsorbed secondary antibodies when absolute specificity is required. -
News Sterling Pharma to acquire CiVentiChem in the US
The acquisition will enhance the CDMO's chemistry development capabilities to support pre-clinical and early phase clinical supply. -
News 'Drugs from bugs' joint venture
Lonza and Chr. Hansen create a strategic joint venture to become the partner of choice for developing and manufacturing live biotherapeutic products for pharma and biotech customers. -
News Curcumin and pomegrantes - new hope for Alzheimer’s prevention?
New research at University of Warwick will test how curcumin kick-starts the brain’s cleansing of damaging plaques and cells. -
News MedPharm's appointment with Destiny
Global contract provider to develop new XF-platform drug formulations for the treatment of a number of topically treated infections, including diabetic foot ulcers and ophthalmic infections. -
News Third Sartorius Research Xchange Forum 2019 focuses on CAR-T cell therapy
Event for experts from academia and industry, including talks, live demo sessions, and panel discussion. -
News Envigo launches PATHWAY to enable FIH clinical trials
PATHWAY manages the complexity of the entire safety assessment process on behalf of the company’s pharmaceutical and biotechnology customers. -
News Biogen acquisition boosts its ophthalmology pipeline
Nightstar Therapeutics has two potentially first-in-class mid- to late-stage clinical assets as well as preclinical programs. -
News Uniqsis expands LED photoreactor range
The availability of three new alternative switchable LED configurations provides chemists with the unique ability to optimally undertake almost any photochemistry reaction. -
News Crowdfund and discover promising therapeutics via Molecule
Connecting scientists, patients, and industry to advance drug development in a collaborative open market. -
News Partnership expands to develop a new treatment for pachyonychia congenita
MedPharm and Palvella Therapeutics hope to develop the first approved treatment for PC in the US and Europe. -
News Chemspace and LabNetwork collaborate to extend access to chemical databases
Collaboration provides drug discovery researchers access to European distribution and local support for library of in-stock and on-demand compounds. -
News SGS to conduct its first malaria human challenge trial in Belgium
The advanced candidate compound undergoing the trial has demonstrated potential to target malaria parasites before they have a chance to establish the symptoms of malaria. -
News Andrew Alliance and Sartorius collaborate to provide software-connected pipettes for life science research
Researchers to benefit from an innovative software-connected pipetting system, bringing improved reproducibility and traceability of experiments to life-science laboratories. -
News New API screening program strengthens Particle Sciences' nanomilling offering
Advanced formulation techniques such as nanomilling may provide an excellent route to improved bioavailability and enhanced therapeutic effect. -
News Allergan to establish R&D presence in Cambridge, Massachusetts
The new, strategic presence will allow the company to more easily interact and engage with venture firms and start ups in the area. -
News Expedeon signs supply and license agreement for is Lightning-Link technology
The technology will enable Cell Guidance Systems to manufacture TRIFic detection assays on-demand with highly reproducible and scalable results. -
News Lilly launches new robotic laboratory
Web-based platform provides broad access to the first-ever cloud laboratory to integrate automated biology and chemistry research capabilities in a closed-loop system. -
News Sharing knowledge to improve scientific exchange in UK drug discovery
ELRIG UK and British Pharmacological Society initiate a 2-year strategic alliance. -
News MIT engineers repurpose wasp venom as an antibiotic drug
Altered peptides from a South American wasp’s venom can kill bacteria but are nontoxic to human cells. -
News Spanish CDMO working ahead of EU serialisation deadline
Company now able to serialise commercial batches manufactured by them for clients; it can also offer standalone serialisation services as an outsourcing partner. -
News Fluidic Analytics raises $31m to launch new lab tools and unlock biology behind major diseases
The financing will power the global commercial launch of the company's Fluidity One system. -
News OnDosis and Recipharm partner to advance a novel treatment regimen for ADHD
The new treatment will leverage OnDosis’ proprietary technology, which integrates oral drugs in form of micro units and individualised dosing, in a handheld device. -
News NIH to evaluate effectiveness of male contraceptive skin gel
The gel formulation includes the progestin compound segesterone acetate, in combination with testosterone, and is applied to the back and shoulders and absorbed through the skin. -
News QPS expands US-based Phase I clinical trial capabilities
Expansion supports the growing needs of the company's pharmaceutical, biotechnology and CRO partners. -
News Grant winners to investigate continuous manufacturing for gene therapies
Cobra Biologics, Pall, and the Cell and Gene Therapy Catapult share £1.5 million grant from the UK's innovation agency. -
News Proprietary nasal delivery formulation of diazepam reaches NDA
The absolute bioavailability of the Valtoco intranasal formulation was 96% of intravenous diazepam in a Phase I cross-over trial. -
News Plasticell receives EU funding to advance neurodegenerative disease research
Th company's CombiCult combinatorial cell culture technology will be used to generate high fidelity, progenitor and terminally differentiated neuronal and glial cell subtypes for incorporation into next-generation models. -
News Lonza acquires controlling stake in Octane Biotech to further develop Cocoon autologous technology
Acquisition further strengthens Lonza’s commitment to drive the next generation of manufacturing patient-specific and personalized therapies. -
News SIRIO Pharma opens multimillion gummy production plant
The new ‘Centre of Excellence’ already boasts one of the world’s most advanced gummy production line designed to meet demand from global markets. -
News New formulation modelling successes using ex vivo tissue
One study uses the company's proprietary TurChub model, to evaluate the diffusion and subsequent activity of drugs in human nails. -
News Three-way collaboration to advance gene therapy
Partnership aims to increase the robustness and reduce costs for the manufacturing of AAV vectors. -
News New oral treatment for metastatic melanoma receives EU authorisation
Encorafenib in combination with binimetinib demonstrated 14.9 months median progression-free survival compared with vemurafenib monotherapy (7.3 months). -
News Plasticell wins military contract to develop regenerative medicines for the battlefield
Company to use its combinatorial stem cell screening platform to develop technologies for the conversion of pluripotent stem cells into platelets. -
News New biopharmaceutical testing laboratory to open in Geneva
SGS's expansion will enable the service provider to offer a full ICH Q6B physico-chemical characterization of biological products. -
News Exosome isolation manufacturing and characterization
New service to reliably and reproducibly isolate exosomes from almost any biofluid. -
News Oxford Genetics signs major supply and licensing agreement for CRISPR engineered mammalian cell lines
Company moves away from manual processing in favour of automated, scalable platforms. -
News A new era for migraine patients
EU approves Novartis's Aimovig, a first-of-its-kind treatment specifically designed for migraine prevention. -
News WuXi STA and Antengene sign development and manufacturing agreement
WuXi STA chosen for its end-to-end CMC platform for new drug development. -
News New screening company exploits the latest advances in microfluidics and 3D culture
The ability to micro size drug-cell interactions will allow pharmaceutical and biotech companies to do 100x more testing for the same money spent as well as increasing productivity. -
News ProBioGen and Pionyr initiate 2nd immuno-oncology contract development and manufacturing project
Parallel cell line development and analysis will allow for optimal cell line selection while compressing the development timeline. -
News Natural lipid acts as potent anti-inflammatory
Scientists see therapeutic potential against bacteria, viruses. -
News Plasticell leads gene therapy manufacturing consortium
Consortium to develop advanced technologies for the manufacturing of ex vivo gene therapies. -
News Follicum develops new direct-to-scalp formulation
The topical treatment for hair loss boasts a 'commercial' formulation. -
News Collaboration to provide GMP-based services
Researchers to benefit by receiving a rapid and cost-effective scaled supply of new compounds. -
News Locate Therapeutics secures £2 million to fast-track development of innovative cell therapy programs
TAOS matrix system and products hailed as potential ‘game changers’ in the field of regenerative medicine. -
News Comparative analysis of a complex monoclonal antibody
New poster describes how the EAF4 module enabled simultaneous measurement of size and surface charge characteristics of antibodies and proteins. -
News The shortest way from the lab to continuous production
Bosch's new Xelum R&D for continuous production of oral solid dosage forms ensures a short time-to-market and optimum dosing of APIs. -
News Lilly expands oncology pipeline with acquisition
Acquisition of AurKa Pharma expands Lilly's oncology pipeline with early-phase asset being studied in multiple tumour types. -
News Versatile lyophilizer for research, development or small-scale production
Allows for easy and intuitive scale-up from research. -
News New online customer portal for custom research services
Customers to gain a greater insight into their projects, better track project progress and improve communications. -
News Essential malaria parasite genes revealed
NIAID-funded research could aid antimalarial drug development. -
News WuXi STA to build new R&D center in Shanghai
Integrated one-site solution for partners to push forward innovative APIs and advanced intermediates from preclinical to commercial stage. -
News Manufacturing collaboration to advance PMD-026 toward IND
MD-026 is the first RSK inhibitor to demonstrate potential disease-modifying properties in triple-negative breast cancer. -
News Omega-3s from fish oil supplements no better than placebo for dry eye
NIH-funded study finds omega-3 fails to yield beneficial results in the clinic. -
News Hope on the horizon for hair loss sufferers
First patient treated in Follicum’s Phase IIa study of FOL-005 for stimulation of hair growth. -
News Biogen to acquire first-in-class Phase IIb ready asset for cognitive impairment
PF-04958242 is an AMPA receptor potentiator designed to facilitate neurotransmission. -
News New Cosentyx data look promising for patients with scalp psoriasis
Majority of patients with scalp psoriasis on Cosentyx (secukinumab) achieved clear skin at Weeks 12 and 24 and improved quality of life. -
News Lonza to establish cell- and gene-therapy Centers of Excellence to accelerate growth
The Centers of Excellence will allow custoners to access customer-centric solutions. -
News Expanded GXP compliance increases Concept's breadth of services
Successful MHRA inspection at Dundee site confirms GLP accreditation for in vitro safety studies and bioanalysis. -
News 'Effective' hair loss treatment candidate advances to Phase IIa
German Medicines Agency sees potential in FOL-005 - a modified version of the endogenous protein, osteopontin - the green light for further studies. -
News Metrion Biosciences awarded £200k funding to further develop in-house drug discovery pipeline
Funding will support further development of recently acquired small molecule assets for treatment of autoimmune disease. -
News Lab automation systems for faster scientific breakthroughs
PAA showcases its complete range of automation solutions, suitable for any type of laboratory or application, at SLAS2018. -
News Sanofi, DNDi seek EMA review for sleeping sickness treatment
Fexinidazole would be first all-oral treatment under investigation for both first and second stages of sleeping sickness, a fatal disease, endemic in Africa. -
News Collaboration expanded to explore synthetically feasible chemical space
Enamine REAL database of synthetic compounds accessible via UCSF’s online ZINC platform. -
News Partnership in AI and machine learning for target discovery
LifeArc and Milner Therapeutics Institute to develop, validate and integrate cutting-edge machine learning approaches into drug discovery processes. -
News Charles River acquisition enhances discovery expertise
KWS increases Charles River's ability to support clients’ early-stage drug research in critical therapeutic areas. -
News 2017: A year of innovation and advances
A summary and highlights of new drug therapy approvals and other drug therapy advances in 2017 by FDA's CDER. -
News New automated VPT systems for topical drug performance testing
The MedStat-HT and MedFlux-HT help to de-risk development programs and shorten development timelines. -
News 3D human sebaceous glands technology for skin care applications
New 3D technology provides a powerful platform for skin care researchers wishing to study the function of sebaceous glands, in relation to a range of age-related, microbial and inflammatory skin disorders. -
News Sangamo and Pfizer collaborate to develop zinc finger protein gene therapy for ALS
"The precision and flexibility of zinc finger proteins enables targeting of virtually any genetic mutation." -
News Promacta receives FDA Breakthrough Therapy designation for first-line use in severe aplastic anemia
Data supporting designation showed over half of treatment-naïve SAA patients achieved complete response with Promacta when given with standard immunosuppressive therapy, with overall response rate of 85%. -
News Momenta and Mylan to development proposed biosimilar to Eylea
Targeting the initiation of a pivotal patient clinical trial in the first half of 2018. -
News Novartis Kisqali receives FDA Breakthrough Therapy designation
Designation based on Phase III MONALEESA-7 results demonstrating superior efficacy of Kisqali in combination with oral endocrine therapy compared to oral endocrine therapy in pre- or perimenopausal women who received no prior endocrine therapy for adva... -
News Scholar Rock announces $47 million Series C financing to advance innovative pipeline
SRK-015 to move into clinical development for Spinal Muscular Atrophy (SMA) in first half of 2018; development in additional neuromuscular disorders to follow. -
News Novel Sorrento CAR-T technology a potential “game-changer
Company envisions the development and IND filings of multiple “next-frontier” CAR-T programs in 2018 and beyond, which will position the company as a potential major player in the fast-growing CAR-T space of immunotherapies against cancers. -
News Novartis' combination therapy Tafinlar + Mekinist granted FDA Priority Review
If approved, Tafinlar + Mekinist expected to be the first adjuvant targeted therapy combination to demonstrate a significant clinical benefit in patients with a BRAF V600 mutation. -
News FDA accepts NDA filing for Epidiolex in the treatment of Lennox-Gastaut syndrome and Dravet syndrome
The PDUFA goal date for completion of the FDA review of the Epidiolex NDA is 27 June 2018. -
News Novartis drug Tasigna approved by FDA
First and only CML therapy with Treatment-free Remission data in its label. -
News MAA submitted to EMA for patisiran for the treatment of hereditary ATTR amyloidosis
Sanofi and Alnylam's patisiran MAA to be reviewed under accelerated assessment. -
News AMSBIO introduces highly efficient substrate for culturing ES/iPS cells
iMatrix recombinant Laminin-511 E8 protein fragments permit ES/iPS cells to be maintained in xeno-free, feeder-free culture conditions enabling easy application in medical trials. -
News FiH trial of new immunotherapy approach shows efficacy in antibiotic resistance
Human polyclonal antibodies show promise as effective treatment. -
News Biogen and Ionis collaborate to identify novel therapies for the treatment of SMA
New collaboration agreement to identify new antisense oligonucleotide drug candidates. -
News FDA clears myPKFiT for ADVATE to help personalize care for hemophilia A
First and only FDA-cleared PK dosing software to support healthcare professionals in creating personalized dosing regimens for patients 16 and older with hemophilia A. -
News Collaboration to develop innovative technologies
Project will innovate technologies in epigenetic characterisation for patient stratification in renowned precision medicine. -
News NIH study uncovers clues about why common cancer drug causes hearing loss
Researchers find target to protect hearing during chemotherapy treatment. -
News Regeneron and ISA Pharma to advance immuno-oncology treatment
Collaboration to conduct clinical trials of the combination treatment in both cervical and head-and-neck cancer. -
News Major breakthrough for new haemophilia A treatment
Drug trials provide mind-blowing results. -
News New formulation of Oncaspar receives Marketing Authorization in Europe for patients with ALL
Freeze-dried, or lyophilized, formulation aims to improve supply management by providing the same dosing regimen as liquid Oncaspar but with a three-times longer shelf life of up to 24 months. -
News CMC Biologics and Harpoon Therapeutics collaborate on exciting new TriTAC molecules
First clinical candidate, HPN424, is in development for the treatment of metastatic prostate cancer and expected to enter Phase I clinical trials in 2018. -
News Sanofi ends development of Clostridium difficile vaccine
IDMC concludes that the study is unlikely to meet its primary objective. -
News Novartis' Ultibro Breezhaler significantly improved COPD patients' lung function after direct switch from Seretide
Study provides further evidence that it is possible to reduce the burden of long-term inhaled steroids in many COPD patients. -
News Company's new identity integrates services typically found in disparate CDMOs and CROs
Quotient Sciences Translational Pharmaceutics platform integrates formulation development, real-time adaptive GMP manufacturing and clinical research. -
News New treatments to solve global antibiotic crisis could reach the market by 2020
New ARB technology rejuvenates existing antibiotics to outsmart antibiotic resistance. -
News Bavencio becomes first treatment for rare skin cancer mMCC licensed for use in the UK
The launch of avelumab marks a step-change in the way that mMCC can be treated. -
News Novartis seeks leadership with Cosentyx
For the first time for any biologic, data show almost 80% of ankylosing spondylitis patients on Cosentyx have no radiographic progression of the spine at 4 years. -
News NousCom raises €42 million to develop off-the-shelf cancer vaccine
Financing to advance its pipeline of neoantigen cancer-based immunotherapies to the clinic. -
News RA patients treated with baricitinib reported greater improvements in pain compared with adalimumab
Post-hoc analysis shows pain improvement was consistent regardless of a patient's baseline pain severity. -
News RedHill Biopharma and IntelGenx submit NDA to FDA for Rizaport for migraines
Rizaport is a proprietary oral thin-film formulation of rizatriptan for the treatment of acute migraines. -
News Cristal Therapeutics progresses nanomedicine CriPec-docetaxel to Phase Ib development
This nanomedicine candidate is specifically designed to enable enhanced tumour accumulation and local drug release at the target site, to boost the therapeutic efficacy and to overcome the shortfalls associated with current docetaxel products. -
News FDA approves AstraZeneca's Calquence for adult patients with mantle cell lymphoma
Accelerated approval of Bruton tyrosine kinase inhibitor in MCL marks AstraZeneca's entry into the treatment of blood cancers. -
News NIH study identifies new targets for anti-malaria drugs
The deadliest malaria parasite needs two proteins to infect red blood cells. -
News Arch Biopartners initiates manufacturing process for Metablok
In pre-clinical studies, Metablok has shown it has the ability to prevent acute kidney injury by blocking the inflammatory response triggered by kidney ischemia/reperfusion. -
News SGS and Bavarian Nordic to develop a novel and differentiated challenge model for RSV
Project will build upon the results of Phase II trials undertaken by Bavarian Nordic. -
News PnuVax awarded $29.4 million grant to advance innovative vaccine into clinical trials
Use of PnuVax’s unique patented conjugation platform technology to produce the vaccine is expected to speed up biomanufacturing and increase yield for a greatly reduced per-dose cost.
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