ADC Linker & Payload Chemistry

ADC Linker & Payload Chemistry
Product Description

AAPharmaSyn supports antibody-drug conjugate and bioconjugation programs through small-molecule chemistry focused on linkers, payloads, and linker-payload intermediates. Services include synthesis of cleavable and non-cleavable linkers, functionalized linkers and spacers, custom linker modifications, payload intermediates, and complete linker-payload constructs needed for research and development programs.

The team can also prepare ADC-related reference standards and impurities, troubleshoot difficult linker or payload chemistry, and scale selected intermediates when additional material is required. This chemistry support is designed to complement downstream conjugation and biological evaluation activities.

AAPharmasyn

  • Country/Region:
    United States
  • Founded:
    2006
  • On CPHI since:
    2019
  • Employees:
    1 - 24
Company types
Contract Research Organisation (CRO)
Primary activities
Contract Research Organisation
Specifications
  • Details
    ·       ADC linker synthesis

    ·       ADC payload synthesis

    ·       Linker-payload synthesis

    ·       Functionalized linker synthesis

    ·       Cleavable linker synthesis

    ·       Non-cleavable linker synthesis

    ·       Spacer synthesis

    ·       Linker intermediate synthesis

    ·       Payload intermediate synthesis

    ·       Custom linker modification

    ·       Linker-payload conjugation chemistry

    ·       ADC-related reference standards

    ·       ADC-related impurity synthesis

    ·       Small-molecule chemistry supporting bioconjugation programs

    ·       Scale-up of linker and payload intermediates

  • Selling Points
    Guarantee/Warranty; Place of Origin; Quality Service; Reputation
  • Model
    Fee for Service
  • Supplied from
    United States

AAPharmasyn

  • Country/Region:
    United States
  • Founded:
    2006
  • On CPHI since:
    2019
  • Employees:
    1 - 24
Company types
Contract Research Organisation (CRO)
Primary activities
Contract Research Organisation

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