ATB-301

ATB-301
Product Description

[TGF-β2 Targeting ASO (TASO) + IL-2 Combination therapy] - Phase Ib

1. Confirm the potential of TGF-β2 as a biomarker in human blood and tumor tissues from the efficacy result of Phase Ib clinical trial on cancer patients 

2. Confirm the suppression of IL-2’s side effect in combination therapy which is caused by increase of Treg 

3. Confirm the synergistic effects and mode of action of the combination therapy in in-vivo and Phase Ib clincal study T

4. Secure the safety and efficay of TGF-β2 targeting ASO by monotherapy upto phase 2 clinical trial
- No hepatotoxicity, skin toxicity, or cardiototicity were shown, which are common in Pan TGF-β inhibitors (small moldeules to block TGF-β signaling pathway, antibody against TGF-β1, 2, 3) 

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Autotelic Bio

  • Country/Region:
    Korea, Republic Of
  • On CPHI since:
    2021
  • Employees:
    25 - 49
Company types
Manufacturer/Innovator
View company profile
Categories
more categories Show less

Autotelic Bio

  • Country/Region:
    Korea, Republic Of
  • On CPHI since:
    2021
  • Employees:
    25 - 49
Company types
Manufacturer/Innovator
View company profile

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Autotelic Bio resources (1)