Antisense, RNA
Antisense, RNA Companies (15)
Antisense, RNA News
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News Bill & Melinda Gates Foundation to boost mRNA vaccine initiatives in Africa with USD $40m
To address vaccine inequality and accessibility issues, the Bill & Melinda Gates Foundation aims to deliver USD $40m to various biotech companies and vaccine manufacturers in support of mRNA vaccine development.
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News Revolutionising cancer treatment with mRNA-based therapeutics
Global market for mRNA-based oncology therapeutics expected to reach USD $2 billion by 2029, with promising results for the combination of mRNA candidates with immune checkpoint inhibitors to treat solid tumours.
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News Delivering on mRNA-based therapeutics: innovations in applications and packaging
Since the onset of the COVID-19 pandemic, the innovative potential of mRNA vaccines and therapeutics has raised questions regarding their manufacturing, packaging, and storage/transportation. Learn about how the pharmaceutical supply chain is meet... -
News A United Cause: strategic partnership between BioNTech and the Government of the UK announced
A multi-year collaboration between BioNTech and the Government of the United Kingdom will see the expansion of the company’s presence in the UK, focusing on areas like cancer immunotherapies and infectious disease vaccines.
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Antisense, RNA Products (38)
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Product DeTrityl® Ultrapure
Oligonucleotide manufacturing typically involves protection of the 5′-hydroxyl group with 4,4′-dimethoxytrityl (DMT), which is removed with dichloroacetic acid (DCA) during the detritylation step. CABB’s proprietary catalyst and manufacturing technology inherently minimizes critical impurities, enablin...
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Product Oligonucleotides
Sumitomo Chemical has unique manufacturing technology for high-purity oligonucleotides up to 400mer. We guarantee the highest purity, the shortest lead-time to GMP production and unmatched analytical capabilities alongside strong regulatory support. Make no compromises and work with the wor...
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Product Large Molecule Discovery & Development Services
We provide a wide range of discovery and development services for New Biological Entities (NBEs) from our state-of-the-art facility located in Hyderabad, India. At the core of NBE services is a talented team of scientists experienced in the design and delivery of a range of advanced therapeutic modalities ...
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Product Generic / Monomer
1. Generic ST Pharm focusing on technical challenging and brand generics. We specialize in MRI contrast agents and and possess a portfolio of tuberculosis and anti-infectious drugs as generic APIs. 2. Monomer ST Pharm offers a one-stop service from nucleosides to phosphoramidites with specialty and commo...
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Product Intertek Pharmaceutical Services
To meet your unique pharma and biopharma outsourcing needs, Intertek delivers quality and safety through pharmaceutical contract laboratory services, regulatory support, and supply chain assurance. We bring quality and safety to life!
With our pharmaceutical experts working with you at ...
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Product DMT-2′-O-Methyl-rG(iBu)-CE-Phosphoramidite
DMT-2′-O-Me-rG(iBu)-CE-Phosphoramidite is a high-purity RNA phosphoramidite monomer used for the solid-phase synthesis of 2′-O-methyl-modified guanosine residues in RNA, siRNA, antisense oligonucleotides, and mRNA constructs. The 5′-DMT group, isobutyryl (iBu) base protection, and cyanoethyl (CE) phosphate...
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Product Oligonucleotide CRDMO Platform
WuXi TIDES has a robust and integrated Oligo API Platform, offering R&D and manufacturing services from preclinical to commercial scale and operating out of our US FDA inspected facility based in Changzhou, China. We support the development and manufacture of a variety of oligonucleotide modalities inc...
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Product CordenPharma BotaniChol® Plant-Based Cholesterol
Chemists at CordenPharma and the Otto-von-Guericke-University of Magdeburg, Germany developed a scalable synthesis of pharma-grade cholesterol based on botanical sources. This offers a large-scale production of highly needed cholesterol, which is used as part of the lipid cocktail ...
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Product DNA/RNA synthesis services
rimers and hydrolysis probes - scale depends on the client's needsRNA molecules - up to 2 mg/mlDNA molecules - up to 500bp
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Product Nusinersen
Antisense Oligonucleotide. Used for the treatment of spinal muscular atrophy (SMA), first approved RNA-targeted therapy
Polymorphic form: Amorphous
Documentation: DMFA EU, DMA US, CADIFA
Samples: Available
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Product Phosphor-amidites
amidites are the building blocks for Oligonucleotides. Primopus produces high volume, high quality, large scale batch-sizes for higher volume Oligo applications.Supply chain backward integrated with our parent company Deccan Fine Chemicals in India.
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Product Pseudouridine
Pseudouridine: Pseudouridine 5′-monophosphate sodium salt
Pseudouridine 5´-diphosphate sodium salt
Pseudouridine 5´-triphosphate sodium salt
All products are also available in free form or liquid form upon request.
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Product ATB-810
ATB-810 is a first-in-class antisense oligonucleotide (ASO) candidate for the treatment of ALS and progressive multiple sclerosis. Powered by Autotelic Bio’s proprietary C-Duplex™ technology, it is designed to achieve broad brain distribution and improved tolerability, with compelling efficacy demonstrated...
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Product Oligonucleotide CDMO
ST Pharm offers top-tier customized oligonucleotide CDMO services under stringent cGMP conditions. We enhance raw material supply chain resilience by leveraging in-house manufacturing capabilities of nucleosides/phosphormaidites. Our two state-of-the-art facilities, expected to reach a 7.0 mol capacity b...
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Product mRNA Characterisation and Analysis
mRNA Characterization & Analysis: We support vaccine and therapeutic development through detailed characterization and analysis of mRNA, including assessments of clinical translation efficiency and immunogenicity. At our GLP / GCP / GMP laboratories, scientists can test a mRNA drug substance or drug pr...
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Product Oligonucleotide Analytical Development Services
Analytical Development for Oligonucleotides: For oligo-based drugs, our services span from GLP bioanalysis to GLP/cGMP characterization, supporting development with robust analytical expertise. We support product development, from quality control testing of amidite starting materials and early stage produc...
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