DMT-2′-O-Methyl-rG(iBu)-CE-Phosphoramidite

DMT-2′-O-Methyl-rG(iBu)-CE-Phosphoramidite
Product Description

DMT-2′-O-Me-rG(iBu)-CE-Phosphoramidite is a high-purity RNA phosphoramidite monomer used for the solid-phase synthesis of 2′-O-methyl-modified guanosine residues in RNA, siRNA, antisense oligonucleotides, and mRNA constructs. The 5′-DMT group, isobutyryl (iBu) base protection, and cyanoethyl (CE) phosphate protection ensure high coupling efficiency, excellent stability, and reproducibility in automated oligonucleotide synthesis. The product is suitable for research, preclinical, and GMP manufacturing applications, depending on grade.

Chengda Pharmaceuticals Co. Ltd

  • Country/Region:
    China
  • On CPHI since:
    2015
  • Certificates:
    4
  • Employees:
    500 - 999
Company types
CMO/CDMO
Specifications
  • CAS Registry Number
    150780-67-9
  • Details
    Product Name DMT-2′-O-Me-rG(iBu)-CE-PhosphoramiditeCAS No. 150780-67-9Molecular 
    Type RNA Phosphoramidite Monomer 
    Appearance White to off-white solid or viscous oil
    Purity (HPLC) ≥ 98.0% (Typical ≥ 99.0%)
    Assay ≥ 98.0%Water Content (KF) ≤ 1.0%
    Coupling Efficiency ≥ 99.0%
    Base Protection Isobutyryl (iBu)5′-Protection DMT (Dimethoxytrityl)Phosphate Protection Cyanoethyl (CE)
    Solubility Soluble in anhydrous acetonitrile
    Stability Moisture-sensitiveStorage −20 °C, under inert gas, protected from light
    Shelf Life 24 months under recommended storage
    Grade Available RUO / High-Purity / GMP Packaging
  • Selling Points
    International Approvals/Standards
  • Model
    CD-OMe-rG(iBu)-CE-PA-GMP
  • Supplied from
    China
  • Measured In
    kilogram

Chengda Pharmaceuticals Co. Ltd

  • Country/Region:
    China
  • On CPHI since:
    2015
  • Certificates:
    4
  • Employees:
    500 - 999
Company types
CMO/CDMO

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