Rapid adoption of Carterra’s LSA instrument drives European expansion

20 Aug 2019

Company's antibody screening platform minimizes the risk of missing a blockbuster.

Carterra has opened a Customer Experience Center (CEC) and office in Munich, Germany. Rapid European adoption of Carterra’s platform has fueled the need for the new office.

Rapid adoption of Carterra’s LSA instrument drives European expansion

The Munich CEC will be a place for researchers throughout Europe to gain first-hand experience with Carterra’s game-changing antibody screening platform, the LSA, through demonstrations and workshops. Carterra will also offer basic courses in label-free biosensor operation, experimental design, and data analysis. Since its launch in 2018, the LSA is installed on three continents and in a majority of the largest pharmaceutical companies in the world. To support this exponential worldwide growth, Carterra has hired direct sales, support, and service personnel in Europe, most of whom are based in the Munich office.

Traditional antibody discovery requires a primary screen of ever-expanding antibody libraries by low-resolution “yes/no” assays to identify binders. Only a small group of candidate antibodies are then characterized on traditional, low-throughput biosensor tools, which provide real-time readout of the full binding profile. This workflow runs the risk that potential blockbuster drug candidates could be missed.

Carterra’s LSA is turning that model on its head by enabling the high-resolution analysis of entire libraries, combining screening and characterization into one seamless step, thereby minimizing the risk of missing a blockbuster. The LSA’s dramatic throughput condenses months of work into days.

Additionally, the LSA offers investigators the most resolved view of the epitope – the location an antibody binds to its target. An epitope is an innate property that cannot be changed and must be discovered empirically. The LSA is the only technology that enables characterization of epitope binding at the full library level. This provides biologics developers an enormous advantage in differentiating their biomolecules from competitors’ drugs and in establishing intellectual property claims.

“The LSA is changing the way biologics are discovered,” says Tim Germann, Carterra’s Chief Commercial Officer. “We’re thrilled to invite European drug developers and the research community at large to experience in person the massive throughput and minuscule sample requirements that the LSA enables. We’re making the traditional discovery processes up to 100 times faster while using only 1% of the normal sample input-it’s the definition of disruptive.”

Read More

Related news

Novartis receives EC Approval for next-gen anti-VEGF treatment for wet AMD

Novartis receives EC Approval for next-gen anti-VEGF treatment for wet AMD

21 Feb 2020

Beovu is the only anti-VEGF treatment approved in Europe for wet AMD that offers the option to start eligible patients on 3-month dosing intervals immediately after the loading phase.

Read more 
Catalent to manufacture first-in-class mAb targeting solid tumours

Catalent to manufacture first-in-class mAb targeting solid tumours

11 Feb 2020

ZM008 could have potential benefits for the treatment of prostate cancer.

Read more 
BD completes clinical trial for its wearable injector

BD completes clinical trial for its wearable injector

11 Feb 2020

The pre-filled, pre-assembled injector is designed to prioritize safety, convenience and usability while delivering high-value drug treatments in the comfort of an in-home environment.

Read more 
New Velesco Pharma clinical manufacturing facility begins operations

New Velesco Pharma clinical manufacturing facility begins operations

5 Feb 2020

The facility will triple the company’s cGMP clinical trial manufacturing capacity.

Read more 
Inovio and Beijing Advaccine to advance vaccine against Coronavirus

Inovio and Beijing Advaccine to advance vaccine against Coronavirus

30 Jan 2020

Agreement will facilitate clinical trial translations in China.

Read more 
First human trial of monoclonal antibody to prevent malaria opens

First human trial of monoclonal antibody to prevent malaria opens

28 Jan 2020

If proven safe and effective, mAb CIS43LS might be used prophylactically by tourists, medical workers or military personnel who travel to areas where malaria is common.

Read more 
Thermo launches next-generation, compressor-free plate sealer

Thermo launches next-generation, compressor-free plate sealer

28 Jan 2020

Features new functionalities and capabilities making it versatile for a variety of both manual and automated microplate processing life science applications.

Read more 
Merck invests in biotech development facility in Switzerland

Merck invests in biotech development facility in Switzerland

27 Jan 2020

€250 million to be invested during the 2019-2022 period in new facility bridging research and manufacturing.

Read more 
Grey Wolf Therapeutics secures funding for cancer therapies development

Grey Wolf Therapeutics secures funding for cancer therapies development

21 Jan 2020

The company targets ERAP antigen presentation pathways with the aim of ‘illuminating’ non-responsive tumours for attack and destruction by the immune system.

Read more 
Diabetes diagnosis - now a matter of sweat and tears?

Diabetes diagnosis - now a matter of sweat and tears?

21 Jan 2020

No need to draw blood; researchers develop smart technology to diagnose diabetes and treat diabetic retinopathy.

Read more