8
Oct
2024

MERCK

Exhibitor at CPHI Milan 2024 stand 22D58, Integrated Pharma
About Us

Merck is a leader in life science. Our integrated offering supports all stages of pharma and biopharmaceutical manufacturing from process and formulation materials, single-use manufacturing, filtration, process development, process analytical technologies, to contract manufacturing services - all with extensive regulatory documentation.

Our CTDMO services provide a streamlined experience in a single partner for mAbs, HPAPIs, ADCs, mRNA, and LNP formulation. Our standalone contract testing and analytical development services ensure the safety of the world’s therapeutics. 

Visit https://www.sigmaaldrich.com/DE/en 

  • FR
  • 2020
    On CPHI since
  • 4
    Certificates
  • 5000+
    Employees
Company types
Biopharmaceutical company
Primary activities
Biopharmaceutical
Contract Manufacturer
Laboratory, Analytical, Biotechnology Equipment
Contact info
Event information
CPHI Milan 2024
  • 08 Oct 2024 - 10 Oct 2024
  • Fiera Milano, Italy
  • Visit us at stand 22D58, Integrated Pharma

Products Featured at CPHI Milan 2024

  • (R)-1,2-di-O-octadecenyl-3-trimethylammonium propane chloride 

    Product (R)-1,2-di-O-octadecenyl-3-trimethylammonium propane chloride 

    Cationic lipid used in the preparation of liposomes and lipoplexes. Specifically, R-DOTMA chloride with its positive charge allows the protective loading of nucleic acids into lipid nanoparticles and promotes their endosomal release. Merck as the solely manufacturer of DOTMA-Cl can provide you with high-pu...
  • 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine 

    Product 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine 

    Based on our unique lipid processing and isolation techniques Merck’s helper lipid DOPE demonstrates outstanding solubility and thus distinctive physico-chemical properties in comparison to conventional amorphous DOPE’s. Those improved handling properties facilitate your LNP formulation process 
  • ADC & Bioconjugation CDMO services

    Product ADC & Bioconjugation CDMO services

    With 15+ years of contract development and manufacturing experience, Millipore® CTDMO Services offers leading expertise in the conjugation of drug linkers to monoclonal antibodies (mAbs). As ADC and Bioconjugation CDMO, we have comprehensive experience in conjugation technologies backed by broad analytical...
  • API Processing portfolio

    Product API Processing portfolio

    Choose API processing to improve API properties right from the start and avoid the risk of dealing with a poorly water-soluble API in formulation development or the need to start API development from scratch.

     

    Whichever API processing method you decide to use, we pr...
  • Benzonase® endonuclease portfolio

    Product Benzonase® endonuclease portfolio

    Benzonase® endonuclease is a unique, genetically engineered endonuclease that offers a variety of advantages over existing methods of nucleic acid removal. This enzyme has been designed to be supplied without protease activity and without the viral contaminants that can accompany enzymes isolated from ...
  • Biosafety Testing & Analytical Development Services

    Product Biosafety Testing & Analytical Development Services

    Choosing the right partner for analytical and biosafety testing is critical in the race to approval. Our BioReliance® Contract Testing Services offer exceptional, risk-mitigating solutions with technical and regulatory expertise, to help bring life-changing drugs to market.
  • Cellicon®  Perfusion Filter and Controller

    Product Cellicon® Perfusion Filter and Controller

    A Superior Cell Retention Solution for N-1 Seed Train Intensification with Optimized Process Control. The benchtop Cellicon™ Perfusion Solution is designed to meet your perfused seed train challenges. It consists of a controller and a flat sheet cell retention filter with a single-use assembly running in t...
  • Cellicon® Cell Retention Solution for Process Scale

    Product Cellicon® Cell Retention Solution for Process Scale

    Increase Your Bioreactor Productivity with our superior solution for upstream process intensification. In combination with your bioreactor, the Cellicon® Cell Retention Solution allows you to achieve significantly higher viable cell densities, improving your upstream productivity and manufacturing flexibil...
  • ChetoSensar™

    Product ChetoSensar™

    ChetoSensar™ is our novel solubilization technology for hydrophobic ADCs.

    Increased ADC solubility, important for reaching high DARWider therapeutic index and higher drug efficacyImproved bioconjugation efficiencyChetoSensar™ and ready-to-conjugate drug linkers available as samples or within ADC...
  • Deviron® C16 Detergent EMPROVE® EVOLVE

    Product Deviron® C16 Detergent EMPROVE® EVOLVE

    Deviron® C16 detergent provides robust inactivation of enveloped viruses. In addition, it may be used to achieve cell lysis for viral gene therapy vector production processes. It does not require a REACH authorization and is a suitable alternative to Triton™ X-100  detergent.

  • Dimyristoyl glycerol polyethyleneglycol-2000 

    Product Dimyristoyl glycerol polyethyleneglycol-2000 

    High-purity and high-quality DMG-PEG2000 enabling a consistent supply from development to commercial scales. 
  • DM1

    Product DM1

    A GMP quality payload for your drug-conjugateprogram• Samples available free of charge• Validated analytical methods• Free licensing and no royalty payments
  • DolCore™

    Product DolCore™

    Advanced intermediateEnables rapid synthesis of dolastatin-10 payloads.Suitable for up to phase I clinical studies with process, validation to support path to commercial approval.Contact one of our experts to request a free sample.
  • Exatecan

    Product Exatecan

    A GMP quality payload for your drug-conjugateprogram• Samples available free of charge• Validated analytical methods• Free licensing and no royalty payments
  • mAbs and rProteins CDMO services

    Product mAbs and rProteins CDMO services

    With Millipore® CTDMO Services we provide deep expertise and flexible solutions across all stages of development and manufacturing for monoclonal antibodies, bi-specific antibodies, fusion proteins, or antibody fragments. We work with our clients to balance risk, optimize speed, and support all aspects of ...
  • MAST® Autosampling Solution

    Product MAST® Autosampling Solution

    A Versatile & Modality-Agnostic Aseptic Autosampling Solution for Reliable On-Line and Near Real-Time Sample Analysis  
  • MayCore™

    Product MayCore™

    Advanced intermediateEnables rapid synthesis of maytansine payloads.Suitable for up to phase I clinical studies with process, validation to support path to commercial approval.Contact one of our experts to request a free sample.
  • Meglumine

    Product Meglumine

    Meglumine is a versatile product applied either as a counterion to form a salt with the API or as a functional excipient. Traditionally applied as a counterion in contrast media, meglumine is an organic base which can also be used as a functional excipient to enhance API solubility, improve API stabili...
  • MilliStak+® Depth Filters

    Product MilliStak+® Depth Filters

    Innovative, High-Performance Pod Filters are Ideal for Primary and Secondary Clarification in Lab, Pilot and Process-scale Applications. Millistak+® depth filter media is offered in a scalable, disposable format: the Pod Filter System. 
  • Millistak+® HC Pro Synthetic Depth Filter

    Product Millistak+® HC Pro Synthetic Depth Filter

    Millistak+® HC Pro (high-capacity synthetic media) is a family of synthetic depth filters providing a cleaner and more consistent depth filtration media over current diatomaceous earth (DE) and cellulose (CE) based filter offerings. Multiple media grades are available for primary and secondary clarificatio...
  • MMAE

    Product MMAE

    A GMP quality payload for your drug-conjugateprogram• Samples available free of charge• Validated analytical methods• Free licensing and no royalty payments
  • Mobius iFlex® Bioreactor

    Product Mobius iFlex® Bioreactor

    The next generation of high performance single-use modular bioreactors for fed-batch and perfusion processes
  • Mobius® Breez Microbioreactor System

    Product Mobius® Breez Microbioreactor System

    The Mobius® Breez Microbioreactor is a 2 mL automated single-use perfusion cell culture platform designed to support gentle, adaptable, and reproducible cell processes. The system is capable of accelerating cell line development, media screening and optimization, and early process development
  • Mobius® Gold High Cell Density Cryopreservation Assemblies (-80 °C)

    Product Mobius® Gold High Cell Density Cryopreservation Assemblies (-80 °C)

    A single-use assembly designed to facilitate the freeze and thaw of cryopreserved cells at -80 °C. Mobius® Gold High Cell Density Cryopreservation Assemblies enable seed train inoculation with cells at a higher cell density and larger volume, which significantly accelerates the cell expansion process. The ...
  • mRNA / Lipidic Nanoparticles CDMO services

    Product mRNA / Lipidic Nanoparticles CDMO services

    As part of our Millipore® CTDMO Services offering, we pave the way for robust, integrated, and consistent processes along all stages from pre-clinical to commercialization. Bringing together our capabilities, technical expertise, and regulatory know-how, we enable our clients to achieve their goals— to get...
  • Natrix® Q Chromatography Membrane

    Product Natrix® Q Chromatography Membrane

    Natrix® Q Chromatography Membrane for single-use, scalable purification, Natrix® chromatography membrane is a high capacity, high throughput strong anion exchange device designed to purify biomolecules. It combines the capacity of high performing resins with the exceptional flow properties of chromatograph...
  • Novaseptum® SURe Sterile Sampling Assemblies

    Product Novaseptum® SURe Sterile Sampling Assemblies

    A single-use sterile sampling assembly that takes representative samples while protecting your bioprocess from cross-contamination. NovaSeptum® SURe sampling assemblies can be easily integrated into your single-use manufacturing process. Available in five popular container formats and with two connect...
  • Parteck® MXP (Polyvinyl alcohol 3-82) EMPROVE® ESSENTIAL Ph Eur

    Product Parteck® MXP (Polyvinyl alcohol 3-82) EMPROVE® ESSENTIAL Ph Eur

    Poor solubility of APIs is a critical challenge in the drug development process. Our Parteck® MXP range of polymers includes two polyvinyl alcohol-based excipients, specifically designed and optimized for hot melt extrusion to increase solubility for a broad range of APIs.

    With a lower de...
  • Parteck® MXP (Polyvinyl alcohol 4-88) EMPROVE® ESSENTIAL Ph Eur,ChP,JPE,USP

    Product Parteck® MXP (Polyvinyl alcohol 4-88) EMPROVE® ESSENTIAL Ph Eur,ChP,JPE,USP

    Poor solubility of APIs is a critical challenge in the drug development process. Our Parteck® MXP range of polymers includes two polyvinyl alcohol-based excipients, specifically designed and optimized for hot melt extrusion to increase solubility for a broad range of APIs.

     
    q...
  • Parteck® PLX 188 (Poloxamer 188) (stabilized with 70ppm BHT) EMPROVE® ESSENTIAL Ph Eur,NF

    Product Parteck® PLX 188 (Poloxamer 188) (stabilized with 70ppm BHT) EMPROVE® ESSENTIAL Ph Eur,NF

    Parteck® PLX 188 is a dissolution rate enhancing excipient that also acts as a robust water-soluble, hydrophilic lubricant. With its optimized particle size, Parteck® PLX 188 poloxamer is designed with the needs of modern manufacturing in mind - such as direct compression and continuous manufacturing -...
  • Parteck® SLC 500 EMPROVE® ESSENTIAL Ph Eur,NF

    Product Parteck® SLC 500 EMPROVE® ESSENTIAL Ph Eur,NF

    Parteck® SLC mesoporous silica is a multi-functional excipient for both solubility enhancement and particle engineering.

    When used as a solubility enhancing excipient, the high surface area and small pores of Parteck® SLC mesoporous silica enable optimal stabilization of the more solubl...
  • PBD Core™

    Product PBD Core™

    Advanced intermediate.Enables rapid synthesis of PBD payloads.Suitable for up to phase I clinical studies with process, validation to support path to commercial approval.Contact one of our experts to request a free sample
  • Pellicon® Capsules with Ultracel® Membrane

    Product Pellicon® Capsules with Ultracel® Membrane

    Accelerate your therapy using our innovative single-use tangential flow filters with superior flux performance. Ideal for single-use tangential flow filtration (TFF), Pellicon® Capsules provide high flux and linear scalability in a plug ‘n play format for optimum process flexibility and productivity. Pelli...
  • ProCellics™ Raman Analyzer with Bio4C® PAT Raman Software

    Product ProCellics™ Raman Analyzer with Bio4C® PAT Raman Software

    An Easy-to-Use GMP Process Analytical Technology (PAT) Platform to Monitor Cell Cultures In-Line and in Real-Time, from Process Development to Manufacturing
  • Protein stabilizer portfolio

    Product Protein stabilizer portfolio

    Specifically developed for high-risk applications, our portfolio of high-quality sugars, polyols, amino acids, and surfactants simplifies selection when you face critical challenges such as preventing aggregation during manufacturing.
  • Small Molecule CDMO services

    Product Small Molecule CDMO services

    With Millipore® CTDMO Services we support small molecule API synthesis projects from milligram to commercial quantities. We are the partner to address the most difficult challenges, whether the target is difficult to handle, synthesize, or source. With a true consultative and partnered approach, our servic...
  • Ultimus® Film

    Product Ultimus® Film

    An innovative single-use film offering strength and leak resistance for your toughest liquid bioprocessing applications. Ultimus® film provides enhanced bag strength, improved durability and leak resistance through a novel strength layer reinforced by woven nylon. The inert fluid contact layer promotes hea...
  • Viral Vector CDMO services

    Product Viral Vector CDMO services

    Millipore® CTDMO Services delivers expertise and flexible solutions for viral vector development and manufacturing to advance cell and gene therapies from preclinical through commercial production.

    Our proficiency with adeno-associated virus (AAV), lentivirus, adenovirus, and other vectors helps...
  • Viscosity Reduction Platform

    Product Viscosity Reduction Platform

    The Viscosity Reduction Platform of proprietary excipient combinations enables subcutaneous formulation of highly concentrated protein biologics, bringing together increased concentrations and improved downstream processing.