Trends in Packaging Cosmetics

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The sixth CPHI Annual Survey will explore the perspectives of some 400 pharma executives, evaluating the likely trends in 2023 and the reputations of all major pharma markets. The analysis spans insights from some 35 questions and is a key bellwether of industry prospects in the year ahead. The second component of the CPHI Annual Report – now in its 10th edition – features the detailed analysis of 11 global experts who explore all facets of the industry today and look ahead to predict the major trends

The annual report from Pharmapack 2023 covering the drug delivery market trends across Europe and the US, and how Pharmapack acts as a bridge between the global markets.

Sustainability in pharma is now gaining the recognition it deserves, quickly becoming one of the biggest priorities for pharma companies across the spectrum. Upgrading this Packaging in pharma comes in all shapes and sizes – whether we are talking about replacing single use plastics in manufacturing, or waste management at the end of the commercial chain. Today we will be talking about sustainability in the pharmaceutical packaging industry, how it can be more ingrained and the impact it will have, with an expert from a leading European packaging company, Adelphe. Félicie Pachot is the Health Marketing Manager at Adelphe and she goes into the model Adelphe uses to support sustainable practices through recycling, reduction of waste, and reuse.

In this latest episode from the CPHI Podcast Series, Digital Editor Lucy Chard speaks to Sanjay Sharma, Global Head of Manufacturing, from Dr Reddy’s. Sanjay has over 26 years of experience in roles encompassing sales, the supply chain, and technical operations. Pharma 4.0 is the upgrading of the pharma industry to a more digitalised state, including automation of processes and greater system integration. This has a wealth of advantages, such as leading to greater compliance and quality control in the manufacturing process. Pharma 4.0 also leads to increasing the sustainability of many aspects of the pharmaceutical chain. Dr Reddy’s is a leading pharmaceutical company and is at the forefront of adopting industry 4.0 into their everyday systems. Dr Reddy’s largest manufacturing facility in Bachupally, Hyderabad, India, recently joined the Global Lighthouse Network of the World Economic Forum, a network of over 100 manufacturing companies committed to developing and leading the progression into Industry 4.0 technologies. This commitment from Dr Reddy’s will help to reduce manufacturing costs, production lead time, and energy consumption, as well as increasing the quality assurance throughout the manufacturing process.

In this month’s CPHI podcast, sponsored by Galien Pharma, we focus on the technology behind orally dissolving tablets. The orally dissolving tablet is a solid dosage form that is sometimes viewed as an unsung hero compared to other patient-centric drug delivery systems. ODTs are becoming increasingly important in the pharmaceutical market for both prescription and OTC medications not least because they can significantly improve patient compliance. However, there are various challenges in the formulation process and there is still much room in the space for manufacturing technology innovation. To find out more, tune into this month's podcast with our guest Franklin Delaye, Strategic & Transformation Director at Galien Pharma.

The pharmaceutical industry is brimming with innovation – from biologics such as cell and gene therapies to COVID-19 treatments and precision oncology drugs. And as pharmaceuticals grow more advanced, so too must the drug delivery and packaging solutions that get them safely from the manufacturer to the patient. This is a competitive arena and among all the companies operating in this space, startups are generally seen as the drivers of innovation, often taking high-risk approaches and doing business with greater agility. In this episode, CPHI is joined by Gareth Pearce, founder of Pacifi Ltd, a startup that modifies glass vials with laser technology to create DuoVIAL, an innovative lyophilized drug delivery solution. Gareth takes us through his company’s journey, explains his long-term vision and speaks more broadly about the role events can play in a startup’s path to success. Listen to the full episode now.

An outbreak of zoonotic disease can have devastating economic and social consequences, as evidenced by the COVID-19 pandemic and increasing concern over monkeypox. Defined as a disease that has transitioned from a vertebrate animal to humans, zoonoses account for about 60% of known infectious diseases and 75% of new or emerging infectious diseases. So, what can be done to limit the spread of these diseases and prevent the next pandemic? In the latest episode in the CPHI Podcast Series, we hear from two companies – Chipsafer and SoundTalks - whose products use data analytics and AI to identify diseases in animals at the earliest indication. Chipsafer is a patented platform that detects and tracks anomalies in livestock behaviour, giving farmers earlier warning when disease breaks out in the herd. Joining us to break down how the platform works is Chipsafer’s founder and CEO, Victoria Alonsoperez. Similarly, SoundTalks is a company that provides real-time health monitoring in pig herds, using microphones and sound analytics to detect possible outbreaks of respiratory disease. SoundTalks’ founder Dries Berckmans joins us to discuss. Listen to the full episode now.

Excipients are essential to the formulation of drug products, but their importance in supporting innovative drug development is often underestimated. According to the International Pharmaceutical Excipients Council (IPEC), drugs that have yet to be developed may need more excipients than are currently available to us, and many new treatments are unlikely to succeed without novel excipients. In short – innovation in drug development requires innovation in excipient manufacturing.

However, the lack of an independent regulatory pathway for novel excipients has historically created barriers to their use and discouraged innovation in the excipients space. In this episode Nigel Langley, Chair of IPEC – Americas and Global Technology Director at BASF Corporation, joins us to discuss developments in the novel excipients arena, as well as the pilot review program launched by the FDA last year.

The supplements market is on the rise, with products like vitamins, herbal drinks, and protein powders found in more household cupboards than ever before.

While supplements can be an excellent way to cover deficiencies not addressed by food intake, the wide range of products available in health food shops, pharmacies and supermarkets can be overwhelming for consumers. And while market growth is expected to continue, products such as herbal supplements and CBD continue to face regulatory issues and scrutiny over the soundness of their health claims.

To discuss the latest trends in the supplements space, we’re joined this month by David Ridley, Senior Editor at HBW Insight and host of Over the Counter podcast. He tells us which products surged in popularity during the pandemic, discusses the rise of self-care, and gives an overview of the regulatory environment in Europe.

Partnering with one of northern Europe’s oldest academic universities, Lund University in Sweden, Pharmapack has launched this three-part podcast series, delivering the latest insights on medication packaging innovation and the gathering momentum towards patient‐centric design. In the third and final episode of this three-part series, we talk to Dr Alex Cole, Head of Strategic Marketing, CPI, and Giana Carli Lorenzini, postdoctoral research fellow, Packaging Logistics at Lund University, about how companies should approach the design of senior-friendly self-administered drug devices by putting the patient and their physical and cognitive limitations at the heart of their programmes, and also how to keep older patients involved and engaged at every phase of the development process.

In this episode we delve into the issue of Pharma 4.0 and what steps the industry is taking to transition pharma manufacturing to a much more digitalised model. The pharma industry is constantly seeking new ways of streamlining its manufacturing processes and digitalisation lies at the core of this transition. It is seen as the springboard to a brave new world of pharma manufacturing, driven by smart facilities of the future, big data, artificial intelligence, data integrity, and end-to end integration to name but a few choice descriptors. We speak to Thomas Halfmann (below), Global Head Production IT, NNIT, who sheds light on the numerous opportunities for manufacturing presented by Pharma 4.0 and what impact the current pandemic has had on the digital transition.

In this podcast interview with Fabien Du Fraisse and Deepu Joseph at Quanticate, we delve into the trend of decentralising clinical trials Not only does the transfer of clinical trials more and more away from investigator sites and into volunteers’ homes offer a more patient-centric approach and reduce the burden on caregivers, it also offers up great opportunities for the industry to capture more data. And as the world adjusts to the reality of a prolonged global pandemic and the difficulties of asking volunteers to make physical visits to sites, never has decentralising clinical trials become such a pertinent issue.

In this special roundtable podcast exploring potential opportunities in a post-vaccinated world, we are joined by a panel of three world class experts – Bikash Chatterjee, CEO of Pharmatech Associates; Parrish Galliher, Managing Director, BioProcess Technology Group, a division of BDO USA and Valdas Jurkauskas, PhD, VP Technical Operations at Black Diamond Therapeutics. The panel discusses insights into what new discoveries and technologies might offer the best potential, the approvals we might see in the next few years, and what might be the long-term positive COVID legacies – from speed of innovation and clinical trials, to proprietary information exchange and the global supply chain. To download a copy of the CPHI Post Pandemic Legacy Trends Report, click here: https://www.cphi-online.com/this-special-cphi-report-is-split-into-two-halves-file113613.html

Partnering with one of northern Europe’s oldest academic universities, Lund University in Sweden, Pharmapack has launched this three-part podcast series, delivering the latest insights on medication packaging innovation and the gathering momentum towards patient‐centric design. Podcast Two: How do you apply patient-centric design to clinical packaging? In the second of this exclusive three-part series, we talk to Sascha Sonnenberg, Global Head Business Development, Sharp Clinical Services, and Giana Carli Lorenzini, postdoctoral research fellow, Packaging Logistics at Lund University, who discuss the challenges of introducing better functionality and usability to clinical packaging amid tight constraints and how the latest innovations in this area are driving patient adherence.

Pharmaceuticals discarded in the environment pose a risk to fish and other wildlife, for example by affecting their ability to reproduce, by altering their behaviour in ways jeopardising their survival, or through direct toxic effects. Increased awareness has prompted further investigation, as well as calls and proposals for action to reduce emissions to the environment, in particular to water but also to soil. Incorrectly disposed medicines may also contribute to the serious problem of antimicrobial resistance (AMR). In this podcast we talk to Dan Caldwell, PhD, Toxicology Fellow, Johnson & Johnson and Steve Brooks, Advisor to the AMR Industry Alliance about what progress the industry is making in terms of addressing the multifaceted challenges that the release of pharmaceuticals poses to the environment, looking at all key points within the pharmaceutical lifecycle.

Our online pharma event CPHI Discover is almost upon us! While we’ll be delving into the typical themes of ingredients, manufacturing, supply chain logistics and technology, we’re also going to be examining some newer trends which are impacting on pharma manufacturing and distribution – such as highly politicized issues such as the change of administration in the US and Brexit and of course, the sector’s drive towards sustainability. In this podcast, Informa Markets’ Head of Content, Tara Dougal and Pharma Editor, Gareth Carpenter run the rule over a packed three-day agenda running from 18-20 May of webinars, podcasts and learning labs.

This month we discuss what is driving M&A strategies in the pharma space, paying particular attention to how investors regard the potential for the growing but fragmented CDMO sector The contract development and manufacturing organisation (CDMO) market is projected to grow to just short of $158 billion by 2025 as a CAGR of 6.9%, amid increasing appetite from biopharma and pharma companies to outsource their manufacturing. In many cases, M&A gives companies the opportunity to expand their reach beyond certain geographies or beef up their service offerings with additional capabilities in the development and manufacturing chain. In this month’s podcast, we speak to Kevin Bottomley, partner at global corporate advisory firm focused on healthcare and life science companies, Results Healthcare, about what is driving M&A strategies in the pharma space and whether investors see high potential for the highly fragmented CDMO sector.

Healthcare provision is constantly evolving. Whereas in the past, decision making on treatments for patients was very much the domain of physicians and doctors, patients now feel more empowered to be involved in the decision making process. The healthcare industry is fully aware of this change and sees a constructive partnership and dialogue with patients as the best way of achieving better health outcomes. In this podcast, we discuss with Nicholas Brooke, founder and executive director of The Synergist and founder of Patient Focused Medicines Development how the concept of patient engagement has developed and what tools are becoming available for meaningful patient engagement in the drug and medical devices development process.

Cannabinoids have caught the attention of Pharma and Cosmetic companies alike in recent years, celebrated for their anti-inflammatory, anti-oxidant and anti-bacterial properties in cosmetic products, and neurological and chronic pain benefits on the pharma side. There is also rising consumer demand for cannabinoids, exacerbated by a shift towards ‘natural’ and toxin free products, which present an interesting opportunity for ingredient manufacturers and producers. In this podcast we speak to Dr. Monica Vialpando, founder and CEO of Via Innovations about the promising applications of cannabinoids, the innovative approaches to product development and formulation, and examining the regulatory and legal considerations of bringing these products to market and whether there is an opportunity for pharma companies to diversify into the cosmetics market. Within this discussion, Dr. Vialpando: 1) Describes what cannabinoids are and why pharma and cosmetics companies are currently investing heavily in their research 2) Shares some key learnings from her transition from a pharmaceutical background into the cannabis industry busts some myths about the origins of cannabinoids 3) Highlights key areas in pharmaceuticals and cosmetics where cannabinoid research is most likely to reap dividends explains where the current research focus on cannabinoids is and how can this be applied to the pharmaceutical and cosmetics industries 4) Provides advice on the key considerations you have to make when designing and branding cannabinoid/CBD-based products

As more and more companies operating in the pharmaceutical space are moving into cosmetics, the temptation is to think that life will be much easier from a regulatory and compliance perspective. However, while it is true that pharmaceuticals are more heavily regulated, this does not mean that cosmetics developers can rest on their laurels. The subtle lines between making marketing claims about cosmetics that are deemed allowable and those crossing the line into drug products can often be blurred. The wrong claims can cause a cosmetic product to be misbranded attracting unwanted attention from the US Food and Drug Administration. In this podcast with John Bailey and Catherine Bailey from EAS Consulting, we take a look at the various common compliance issues that can arise when jumping the boundary from drugs to cosmetics.

mRNA (Messenger ribonucleuc acid) technology has been thrust into the limelight in recent months, with the platform proving to be the springboard for two approved vaccines against the SARS-CoV-2 virus. The complex science around mRNA is very different from that of small molecule traditional pharmaceuticals or traditional biologics such as monoclonal antibodies. This month we speak to Christy Eatmon, Global SME, Sterile Drug Products, Pharma Services Group at Thermo Fisher Scientific about how CDMOs are providing their manufacturing and fill finish expertise to bring mRNA vaccines to market in as timely a fashion as possible.

In this special edition podcast, Informa Markets pharma editor Gareth Carpenter speaks to Bikash Chatterjee, CEO at Pharmatech Associates and Dan Stanton, Editor and Founder at BioProcess International about some of the findings in the recently published CPHI Annual Report 2021, including latest innovations in continuous manufacturing and what is driving growth in the mammalian biomanufacturing sector.

The biopharmaceutical industry has seen incredible growth in the past decade, and shows no sign of slowing as the need for specialised treatments in oncology, immunology and vaccines continue to grow. To support innovation, the biopharma industry needs a suitably skilled workforce, and therein lies one significant challenge facing the market at present. Emerging technologies and new capabilities require a specialized skill-set, and finding the right candidates in a competitive market can be complex. In this month's episode, CPHI speaks to Killian O'Driscoll, Director of Projects at the National Institute of Bioprocessing Research & Training (NIBRT) on some of the key challenges in the biopharma landscape, and why finding the right talent is such a priority for the sector. Listen now to learn more about the biopharma skills-gap, and what can be done to ensure innovation continues at pace.

Smart devices are revolutionising how we live our lives and changing the shape of the industries adopting them. One such industry is healthcare, where the benefits of context-aware devices and real-time data sharing are having tangible effects on patient outcomes. Many smart devices, like wearable monitors, allow doctors to oversee a patient’s health status remotely, facilitating better decision-making and shifting healthcare management from hospitals to homes. But with such rapid technological advancement comes a new challenge: user adoption. In this month’s episode, CPHI speaks to Alex Driver, Senior Industrial Design Consultant at Team Consulting, about breaking down the barriers to smart device access. He shares some of the pain points faced by new smart device owners and outlines strategies for making these accessible to even the most digitally-averse users. We discuss the importance of packaging, the “unboxing” effect and how intelligent design can induce behaviour change. Listen now to learn more about the about the rise of smart devices, and the strategies facilitating onboarding and adoption.

Many companies are turning to M&A to optimise their portfolios and gain access to new technologies, fuelled by an abundance of capital in the sector. These deals can have transformative effects on the companies involved; ideally promoting synergy, diversifying product offerings and improving economies of scale.

This podcast originally aired as part of CPHI Discover - 17-28 May 2021 While hot melt extrusion was developed in the 1930s and initially used in the plastics and food sector, the pharmaceutical industry has now firmly embraced this technology platform in its manufacturing as a way of solving formulation challenges, particularly those around solubility enhancement. Advantages of the approach include the ability to use a wide range of excipients and the ease with which process analytical technology can be incorporated. In this podcast, we explore how HME has developed as a proven technology for bioavailability enhancement of poorly soluble active pharmaceutical ingredients, and how it stacks up against other formulation options in terms of cost and scalability in order to deliver high quality, commercialised pharmaceutical products.

This podcast originally aired as part of CPHI Discover - 17-28 May 2021 Spray drying is used in various pharmaceutical applications and has become an increasingly popular technique in the production of formulations of poorly soluble APIs and inhalable dry powder formulations. This remarkable technology involves spraying a liquid formulation onto a surface which is then allowed to dry to produce a powder in one single step. In pharmaceutical manufacturing, spray drying is suited to the production of peptides, proteins or poorly water-soluble APIs, particularly antibiotics, because it allows them to be co-processed with solubility enhancement excipients. Another advantage is that the approach reduces the number of unit operations, potentially lowering manufacturing costs. This podcast explores how spray drying can overcome the problem of low aqueous solubility that all too often stall clinical testing programmes.

This podcast originally aired as part of CPHI Discover - 17-28 May 2021 Co-crystals are crystalline materials composed of two or more different molecules, typically active pharmaceutical ingredients and co-crystal formers in the same crystal lattice. Tailoring of co-crystals can provide opportunities to not only enhance bioavailability and stability but also the processability of APIs during drug manufacturing. In 2018, the US Food and Drug Administration published guidance clarifying the regulatory classification of pharmaceutical co-crystal solid-state forms for companies planning to submit new drug applications. This move has generated a lot of interest in the co-crystal field. In this podcast, we take a look at how the use of co-crystals have evolved and what are the best approaches to screening and selecting co-crystals to identify the most viable ones to help find suitable development candidates.

In this episode from the CPHI Podcast Series Louise Duffy and Campbell Bunce from Abzena speak to Digital Editor Lucy Chard, using their cumulative knowledge to give an overview of the drug development and manufacturing processes, demonstrating all of the aspects that go into such an undertaking as making a new drug for a patient population. They highlight some of the key areas that teams have to work on, the detailed analysis that has to take place at each stage, as well as within the wider context with regulations to consider, and finally they highlight some of the key areas for innovation and for expanding knowledge in the field. 

In this episode Digital Editor Lucy Chard finds out more about being the Chief Sustainability Officer in the pharmaceutical industry from Nic Hunt, Global Head of Sustainability at Nelipak Healthcare Packaging. In the podcast we discuss what it means to be in the role of a Chief Sustainability Officer, how the role is set to develop along with more established sustainability teams. The role they provide is so integral to the overall health of a pharma company, the pharma supply chain and subsequently the health of the planet. Hunt's optimism about the industry making real changes to how they work and meeting goals such as Net Zero really comes across, with the outlook for the future of sustainability in pharma a bright one.

The podcast focused on the 30 year anniversary of Ursatec in the provision of preservative-free pharmaceuticals, medical devices and cosmetics. We took a look through the Ursatec portfolio, the importance of safety and sustainability in their products, and what the future holds for the company.  Ursatec values the ideology of constant improvement, whether that's keeping patients in mind, or the environment, or both. This is built into the core of the company and the products, the very state of being preservative free demonstrating this holistic vision. 

As part of celebrating International Women’s Day on the 8th March 2023, we wanted to highlight the importance of supporting women’s health. Historically, women’s medicine, in relation to diseases, and sexual and reproductive rights, has been chronically overlooked in the wider field. We hope to use this podcast to open up a wider conversation about educating and empowering women so they can access the healthcare they need.  

This February 28th, we have a special feature episode to mark Rare Disease Day. Rare disease is an oft overlooked field of medicine, but one which is steadily becoming more recognised. Rare diseases affect around 300 million people globally. By their nature, rare diseases are incredibly difficult to research and develop medicines for, but this just makes it all the more urgent to fulfil this unmet need for rare disease patients. In this podcast I am joined by Rachel Smith; Rachel is the Executive Director, Global Head of Rare Diseases at Parexel (MA, USA). Rachel brings more than a decade of experience in every development phase of rare disease and cell and gene therapy clinical trials to her work with Parexel’s rare disease clients. Previously, she served as Vice President of Clinical Operations, Portfolio Director of Rare Disease, and Global Head of the Cell & Gene Center of Excellence at Veristat LLC (MA, USA). She led programmes in ADA-SCID, Canavan disease, congenital adrenal hyperplasia, Fabry disease, Gaucher disease, metachromatic leukodystrophy, and Wiskott-Aldrich Syndrome. Rachel has expertise in clinical development strategy, novel and adaptive trial design, decentralised trials, and other creative solutions for rare disease products with a non-classical route to market.

Join our panel discussion, where out experts will conduct a deep dive through the challenges in drug manufacturing. Key discussion points include: Bottlenecks in skilled workforce and what can be done to overcome this Assessing the challenges in both product and manufacturing quality and identifying solutions to this Reviewing the costs and why it’s a driver to the speed to market. This session was broadcast as part of the CPHI North America show.

Merger, acquisition, and consolidation activity in CRO/CDMO world has intensified to the point where many of my colleagues are beginning to wonder how big the global players can actually become. While many of the mid-sized players have disappeared, a huge number of small pharma service organizations are thriving; creating a giant divide between the small and large players. This also creates a tremendous opportunity for the small pharma service provider to fill the void that’s been created. Today, these entrepreneurial companies are doing incredible science and providing a highly-tailored, fast, and flexible business model to the pharma and biopharma industry. This presentation will take a close look at key market statistics within the smaller pharma services demographic here in the US, as well as a distillation of our findings from discussions with over 200 business owners over the past 18 months. Key questions to be addressed: What are the keys to your current success? What are the barriers to future growth? How has the pandemic impacted your businesses? What are the key risks and opportunities facing the market? This session was broadcast as part of the CPHI North America show.

Originally broadcast as part of the CPHI Monthly Podcasts Series Smart devices and their companion apps are transforming the patient experience and moving healthcare management from hospitals to homes. However, this digital shift can prove challenging for some users. In the latest instalment of our podcast series we speak to Alex Driver, Senior Industrial Design Consultant at Team Consulting, about the creative design solutions increasing accessibility to smart devices. How important is packaging when it comes to user perception? What makes for a good unboxing? And how can manufacturers simplify smart device setup? This session was broadcast as part of the Pharmapack show.

Global drug sales have now hit $1 Trillion for the first time; the R&D pipeline has doubled in the last 10 years, CDMO market is expanding at a consistent 10% YOY. The pharma industry faces countless opportunities; however, there is a problem. Business leaders are asking where has all the talent gone?
This session will explore real-world insights into why the industry is facing a talent crisis. He will share those critical factors any pharmaceutical business should be thinking about when preparing their organization to sustainably grow, including some practical solutions, no matter what your size, to hire more effectively.

This leadership-powered panel discussion will touch upon some of the actions, challenges and the way ahead for producers of fine chemicals to achieve manufacturing excellence through sustainable competitiveness, growth and the promotion of responsible global environmental performance.

BioPhorum has brought together biomanufacturers, supply partners, engineering partners, and regional innovation hubs to build a consensus strategy roadmap, encompassing considerations for all aspects of development from raw material to product, for the future of the industry. The roadmap will be presented alongside recent developments in priority areas agreed by the industry.
These developments facilitate progress for the industry through identifying technology targets and modeling solutions. Current work includes proof of concept demonstrators and business case modeling, plug-and-play hardware, smaller buffer preparation footprints, and driving the move for more standard facility design to accelerate capacity builds.

The demand for localization of pharma products in the countries of the MEA region is booming ! Are the know how and the local infrastructures ready? Is there a clear understanding of the processes? What is the best business model and partnership when it comes to tech transfer? Case Study: Reshaping of KSA pharma business & industry from Importation to Localization

On Demand Pharmaceuticals is creating technology platforms that enable point-of-care medicine manufacturing whether on the battlefield or hospital. By building modular automated systems that can produce raw materials to finished drug product, we are strengthening medicine supply chain resiliency and transforming how patients access medicines. This vertically integrated approach offers agility, flexibility, and a rapid response capability that will mitigate drug shortages while providing quality medicines when patients need them

For the past few years, the traditional one-size-fits-all go-to-market strategy, predominantly based on physical channels, has failed to support drug launches and meet business objectives. Inadequate or incomplete understanding of customer needs has been identified as one of the top-3 root causes.
To optimise patient outcome, biopharma companies need to target and engage effectively with key stakeholders, differentiating the approach based on distinct behaviours and preferences. Our advanced segmentation approach enables to define data-driven HCP segments by leveraging AI and machine learning algorithms. In particular, we display a detailed use case that describes how we have helped biopharma companies leverage data and AI to build differentiated and actionable HCP segments.
Our recommendations detail next best actions to optimize customer engagement and assess the implications on company’s overall level of push marketing actions. Essentially, it will enable to reach the right customers, through the right channel with the right frequency.

More than 75 % of new chemical entities are poorly soluble and require bioavailability-enhancing excipients. The application of excipients in advanced pharmaceutical processes, such as hot melt extrusion and 3D-printing, aligned with advanced approaches towards personalized medicine, requires special features. Lipid-based excipients (LBEs) are “natural contenders” for these tasks. However, until now, it has not been possible to fully exploit the potential of LBEs.
The main challenge is the unstable solid state of current LBEs, e.g. polymorphism, leading to instability of the final dosage form. Compared to polymers, the low melting temperature of lipids, combined with highly crystalline arrangement, limits their application in advanced pharmaceutical processes such as hot melt extrusion and 3D-printing.

With this session you will learn about best practices in Green Chemistry metrics for evaluating the impact of waste in pharmaceutical drug substance manufacturing, and their limitations, in the context of API lifecycle assessment. You will also be informed about the new iGAL 2.0 metric as a valuable extension to the existing waste metrics, allowing evaluation of relative process greenness and the sustainable innovation impact by scientists. Finally, you will learn about opportunities to effectively integrate the new metric into Pharma-CDMO partnerships for the benefit of their business and the planet.
The presentation is based on these recent publications: Improved iGAL 2.0 Metric Empowers Pharmaceutical Scientists to Make Meaningful Contributions to United Nations Sustainable Development Goal 12 | https://doi.org/10.1021/acssuschemeng.1c01940 A Green Chemistry Continuum for a Robust and Sustainable Active Pharmaceutical Ingredient Supply Chain | https://pubs.acs.org/doi/10.1021/acssuschemeng.9b02842

Understanding and channeling ourselves to think about the intersection of sustainability, quality, and supply chain integrity within pharmaceuticals. This relationship has become significant as we enter the post pandemic era in which the pharmaceutical industry strives to not only secure its supply chain and material quality, but in parallel ensure that its sustainable to protect around shortages. This presentation discusses opportunities on how the three sectors align and how through best practices in one area the other two are improved.

Julien Tremblin, European GM of TerraCycle, an innovator in sustainability solutions, shares how companies large and small can drive change, in and out of the pharmaceutical industry and how retailers, brands and consumers are reacting, pushing and adopting as they transition from linear to circular solutions.

Pharmaceutical and Biotechnology companies are exposed to more than their fair share of ESG risks, that, if not addressed properly, can have significant financial and reputational impacts in the long run. To measure a company’s level of exposure with industry-specific material ESG risks and how well a company is managing them, Sustainalytics’ multi-dimensional ESG methodology assesses at least eight different Material ESG Issues (MEIs). Among them, Sustainalytics’ ESG Risk Rating includes Product Governance, Access to Basic Services and Carbon – Own Operations. But what other concepts and indicators should corporate pharmaceutical and biotech professionals consider in their ESG strategies?
Understanding your company’s total ESG risk exposure relies on accurate, independent information, such as reporting, policies and programs to evaluate and improve corporate sustainability. Learn more about how the world’s leading companies leverage Sustainalytics’ ESG Risk Ratings to identify and understand the financially material ESG issues (MEIs) that can affect an organization’s long-term performance.

For the past few years, the traditional one-size-fits-all go-to-market strategy, predominantly based on customer interactions through physical channels, has failed to support drug launches and meet business objectives. Inadequate or incomplete understanding of customer needs has been identified as one of the top-3 root causes. To optimise patient outcome, biopharma companies need to target and engage effectively with key stakeholders, differentiating the interaction based on distinct behaviours and preferences.

In this short webinar, we outline why our advanced digital segmentation approach leveraging AI is the right solution for these challenges and also discuss why it was the right moment for Merck to partner with Deloitte to leapfrog towards data-driven HCP segments. In addition, we talk through what impact can be generated by engaging the right customers, through the right channel with the right frequency and how companies can get started immediately to make the right steps in this direction.

Alessandro de Luca, Group CIO, Head of Information Technology, Merck Group Thomas Bernhardt, Director Life Sciences and Healthcare North and South Europe, Monitor Deloitte Federico Careddu, Manager Life Sciences and Healthcare, Monitor Deloitte Switzerland

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In this webinar is originally broadcast as part of CPHI North America, with speakers Robert Bloder, Chief Business Officer, Ascendia Pharma, Chris Senanayake, CEO & CSO, TCG GreenChem, Inc. and John Pennett, Partner-in-Charge of the National Technology and Life Sciences Group, EisnerAmper. The thread line: The pandemic demonstrated the need for critical life sciences products to be manufactured domestically given supply chain disruptions and reactionary policies from historic suppliers like China and India. At the same time, billions poured into the industry as the US led the race towards developing a vaccine for Covid-19. Two years later, the groundwork has been largely established in terms of increased manufacturing capacity and general industry consensus that domestic production reduces risk, impacting both pharma and biopharma companies as well as CMOs and CDMOs who operate on American soil. But as Covid-generated issues like supply chain delays are gradually elevated, is domestic production here to stay? If so, how will manufacturers keep prices competitive? The panel will dive into current domestic R&D and production capacity, particularly of APIs, and how this influences the CMO sector.

A presentation that discusses novel drug approval trends and how outsourcing propensity is affected by different factors. This session was broadcast as part of the CPHI North America show.

In this webinar, originally broadcast as part of CPHI North America, Marrisa Fayer, Ceo and Founder HerHealthEQ discusses in this session: • Where women are needed more (hint, it's everywhere) • Why having women involved in all aspects of the business makes better business • How to get more women involved • How women's involvement will improve outcomes for your customers • What does this mean for women globally • How this affect better women's health outcomes

In this webinar, originally broadcast as part of CPHI NA, Michael Sassano, CEO and Chairman, Somai Pharmaceuticals discusses: • Global Pharmaceutical Cannabis market and the history of recent growth • Current trends in the Medical Cannabis market versus the Canadian and American experience • Herbal Medicinal Cannabis ACM versus AIM Cannabinoid pharmaceutical trials • Building or conforming to GMP standards for pharmaceutical cannabinoid applications • Single cannabis API versus multiple API combinations - Delivery devices for Cannabinoid products and best practices for bio-availability This session was broadcast as part of the CPHI North America show.

Join us for our 1 hour workshop, where industry experts will discuss the latest B2B marketing strategies in Pharma and what can be done to help evolve and create an omnichannel between CDMO’s and Biotech. This session was broadcast as part of the CPHI North America show.

Recent Congressional proposals have been targeted at drug pricing reform, including opportunities to allow Medicare to negotiate prices for certain drug products, penalizing prices that rise faster than the rate of inflation, and capping out-of-pocket costs for beneficiaries in the Medicare Part D program. This session will explore where the proposals currently stand, what types of drugs are likely to be impacted, and the likelihood of passage of these proposals. Additionally, the session will explore actions that could be taken on drug pricing through the Administration's authority under the Center for Medicare and Medicaid Innovation (CMMI)

In this webinar, originally broadcast as part of CPHI North America 2022, Frances Zipp, President and CEO, Lachmann Consultants Services discusses lessons learned and best practices for these relationships that can be applied to both accelerated approvals as well as “normal” drug supply during non-pandemic times. During normal times, sponsors are often challenged with qualifying outsourced manufacturing services for drugs that receive expedited market entry. However, during the COVID-19 pandemic, multiple products have received EUAs in order to bring them to the market at an even more accelerated timeline in order to address the unprecedented public health crisis of COVID-19. In her talk, Frances Zipp will discuss the quality perspective on these manufacturing relationships and will discuss the checks and balances that need to be in place between sponsors and their outsourcing partners in order to ensure a continuous supply of medicines.

In this webinar, originally broadcast as part of the Pharmapack Europe show, this session is the opportunity to discover new ideas from companies that are at an early-stage and want to know if their product may match the market's expectations. A patented idea can become the next big thing in pharma packaging! Speakers: Gareth Pearce, Founder Director, Pacifi Ltd. Csilla Rimóczi, Head of ECL Business Line, CODEX Ltd. Tristan Salomon, CEO, Axom Francesco Mainieri, Aghetto Thomas Kern, Managing Partner Vinc ,Strategic Life Sciences Transactions Vincent Galand, Expert in Tech for Pharma & Business Development | Busines Angel (Biotech / Medtech), 321funded

Discuss strategies and methodologies to develop scalable, robust, and cost-effective manufacturing processes for allogeneic cell therapies Showcase how induced pluripotent stem cells (iPSC) are being used as renewable sources of allogeneic cancer therapies Demonstrate the criticality of GMP manufacturing capabilities to the success of cell therapies, i.e. leverage biologics manufacturing framework to increase patient access to “off-the-shelf” cellular therapies. This session was broadcast as part of the CPHI North America show.

As the healthcare landscape continues to change, the results can deeply impact the economics of a practice. This session will discuss medical vs pharmacy benefit trends, PBMs, national and government payer changes, and how to stay five steps ahead for community based physicians and infusion centers. This session was broadcast as part of the CPHI North America show.

As global governments and businesses increasingly make bold claims and commitments to tackle the climate emergency, investors are starting to take note by using the ESG framework to move beyond environmental concerns and focus on a company's impact on all the different ecosystems it operates in. The rise of ESG mutual funds Increase market value with SDG targeting. How are your activities impacting growth & profitability? Do you have a clear roadmap to achieve your sustainability goals in each step of the value chain? This session was broadcast as part of the CPHI North America show.

This presentation will focus on: The complexities of bioprocessing and manufacturing of biologics to provide a roadmap for development of effective Efficient and scalable processes and platforms that can be adopted successfully to provide patients wide access to cell and gene therapies. This session was broadcast as part of the CPHI North America show.

This discussion will focus on four critical areas for process development and overall product life cycle management: Quality, Scalability, COGS and Sustainability Strategies for accelerating process development in efforts to initiate clinical trials quicker will also be discussed Examples, from both Imvax and other industry products, will be provided. This session was broadcast as part of the CPHI North America show.

R&D is the lifeblood of Pharma, and the past year has really showcased the tireless work of pharma companies, start-ups and research institutions who have developed treatments, diagnostics and vaccines against COVID-19. Even in pre-pandemic times, the spiraling costs of drug development (estimated at an average ofUSD 2.6 billion*) mean that pharma companies have always had to think strategically about their R&D activities –staying competitive by reducing risk, managing costs and increasing time to market to justify their significant investments. As treatments become ever more complex, how is the R&D model evolving? Should Pharma companies shift from internal R&D to relying more heavily on CROs and other partners to increase the probability of success? What new tools and technologies can the market call upon to reduce risk? This webinar will discuss the evolution of R&D models, the outsourcing landscape, how to de-risk your development and maximise ROI. Discussion Points: Internal R&D Vs Outsourcing Vs M&A Evolving Outsourcing Landscape in Pharma R&D Strategic advantages to outsourcing your R&D needs (Pros & Cons) What factors to consider when selecting an outsourcing partner How much innovation do we see coming from start-ups? How has COVID-19 drug development diverted R&D budgets from other therapeutic areas? The R&D landscape –how can the model be more sustainable? Digital approaches to increasing drug development success WATCH NOW

Increased adoption of digital technologies can offer a multitude of benefits for pharma companies –from data optimization and analysis to increased productivity in R&D, to sourcing candidates for clinical trials. How can pharma companies take a more active approach to implementing digital innovation, to help cope with new challenges in the healthcare industry? One approach to speeding up adoption is to engage with start-ups and established technology companies who can bring different expertise and a more agile approach. This webinar will explore the relationship between Pharma companies and start-ups, as the key to unlocking digital transformation. Why attend? What can digitalization do for Pharma companies? What are the benefits? Has the Covid-19 pandemic accelerated digital innovation in the pharma industry? Partnering for success –how engaging with start-ups and tech companies can help acquire expertise and accelerate development A review of successful solutions, initiatives and Start-Ups helping to solve healthcare challenges What does the future look like? Can we expect to see increased digital transformation?

Building a comprehensive track-and-trace system for medicines, which aligns with the European Falsified Medicines Directive and ensures compliance is a must in today’s environment. Pharmacies, hospitals, HCPs, carers and patients now expect a completely secure and traceable delivery process, which requires buy-in from pharmaceutical companies and distributors involved in the supply chain of Investigational Medicinal Products (IMP), SKU’s and unique doses. This webinar provides an overview of the key trends and developments to improve the security of direct-2-patient drug delivery. Key Discussion Points A global overview of regulations for traceability of medical devices and medicines An overview of global standards that apply to medicines and medical device regulations, as well as to identification of investigational products, locations and business communication in clinical trials Technical challenges when tracking medicinal products along the product life cycle, from clinical trials to post marketing authorization What does the future look like? The potential of delivering Direct-to-Patient unique doses Why attend? Understand global regulations for traceability of drug products and medical devices Get to grips with the technical challenges of tracking medicinal products along the product life cycle, from clinical trials to post marketing authorization Learn what’s next for this sector, and explore the opportunity of delivering Direct-to-Patient unique doses

The webinar addresses the need for new modalities, evolution of bio manufacturing of new modalities, and comparison with semiconductor manufacturing. This session was broadcast as part of the CPHI North America show.

This presentation will provide an overview of the differences and similarities of E&L requirements between pharmaceutical products and medical devices. The key elements regarding E&L testing design of combination products will be discussed. Several case studies on the extractables and leachables testing of combination products will be presented. This session was broadcast as part of the CPHI North America show.

What will this webinar address? Green chemistry strives to reduce theenvironmentalimpact of the manufacture and synthesis of pharmaceutical intermediates for a more sustainable drug manufacturing process. Although the industry has beentaking steps towardsthe application of green chemistryfor drug development and manufacture, there is more to be done on recognizing thecompetitive advantagesof adoption –namely cost benefits, waste reduction, reduced toxicity and increased product yield. This webinar will deliver insights into the key principles of green chemistry, highlight innovative practices in the space and outline the roadmap for adoption, helping your organization towards a more economical and ecological future. Why attend? Understand the foundations and key principles of Green Chemistry Learn how green chemistry can contribute to sustainable development Understand routes to adoption and implementation for both commercial and environmental benefits. What innovation is taking place in the green chemistry arena? What can we learn from innovators and start-ups?

For Pharma Packaging companies who have not yet embedded a sustainable approach into their manufacturing and distribution processes, their hand is now being forced by drug retailers and hospitals who have come to expect more eco-friendly, cost-effective recycling solutions for plastic products and materials used in healthcare delivery. To remain competitive, Pharma companies must now collaborate with suppliers on how their packaging processes address sustainability. This webinar will provide an overview on the drive for sustainable development and improving the recyclability of healthcare products. Key Discussion Points Innovative approaches to sustainable packaging solutions Adopting a value chain approach to meet expectations of hospitals & drug retailers Meeting sustainability goals and remaining cost-effective –the pharma perspective Challenges and sustainable solutions –the supplier’s perspective Why attend? Get the complete overview on the pharma sustainable trends outlook for 2021 in just 60 minutes Hear from experts who share their advices for strategies implementing and best-practices to set-up a collaborative and value-chain approach

Featuring three speakers from leading market intelligence organisations, this webinar outlines the key trends and developments in the pharma sector to be aware of over the coming twelve months. Daniel Chancellor, Thought Leadership Director, Informa Pharma Intelligence, provided a snapshot of pharma pipeline activity during 2020, with oncology being the therapy area that continues to dominate clinical trial activity, with immune and central nervous system jockeying for second and third position.

He also shone a light over the disruption that the COVID-19 pandemic has wrought over trials and the industry’s rapid response to the crisis in terms of developing both vaccines and therapeutics against the virus.

“We have around three and a half thousand clinical trials initiated or planned against COVID-19 since the start of the year, with around 700 pipeline drugs and not to mention some of the repurposed efforts that have been run by academic groups, too,” he told the webinar.

Sarah Rickwood, Vice President European Thought Leadership, IQVIA presented nine key issues that are going to drive change in 2021 and beyond, a blend of some directly accelerated by the current pandemic and others that were issues already in existence prior to the pandemic, “but are really going to see their full impact on changing the shape of pharma and health care in 2021 and beyond regardless.”

She told the audience that the industry is actually dealing with three crises rather than one, and that the first half of the 2020s is likely to be flavoured by the pandemic and its consequences.

“We have the infection crisis, which we hope will be addressed by the vaccines which have come through with such an amazing effort from the pharmaceutical industry,” she said, adding that the challenge is that the infection crisis has triggered two other crises which will stretch through 2021 and beyond.

“The first is a crisis of healthcare systems, the non-COVID treatments of patients in healthcare systems have been delayed, changed and negatively impacted by the fact that healthcare systems have had to pivot to COVID treatment and addressing those patient backlogs which vary by country and by therapy area, is going to take a long period.”

She also pointed to the beginning of the economic crisis, with really worrying drops in GDP in Q2: “The full impact of mass employment has yet to be realized and that will mean health care system budgets will be constrained. So at best I can say is that we’re not living in a post-pandemic environment in 2021, we're living in a vaccine plus environment.”

And rounding off the webinar, Saman Kay, Solutions Consultant for Regulatory Intelligence at Clarivate Analytics, took a look at the future of drug manufacturing technology and assessed the opportunities and challenges of adopting continous manufacturing processes in place of traditional batch manufacturing.

What will this webinar address? There is more emphasis than ever before on biopharma innovation – a sentiment heightened by the speed at which the industry came together to develop vaccines for COVID-19 – setting new expectations for the future. With development comes fulfillment, and with biomanufacturing capacity at an all-time low, what infrastructure is needed to keep pace with innovation? This webinar will provide an overview of biopharma trends and technologies, and address challenges around supply chain, capacity and workforce, to ensure continued productivity, efficiency, and output in the biomanufacturing sector. Key discussion points Biopharmaceutical landscape outlook - what are the short and long-term impacts of COVID-19? Rising trends and technologies – mRNA, immunology, and vaccines Building flexible manufacturing networks and increasing capacity Single-use tech availability Training the workforce of the future Why attend? Get a complete overview of trends, opportunities, and disruptions in the biomanufacturing sector, in just 60 minutes. Hear from experts on shaping biomanufacturing strategies to meet industry needs. Put your questions to our speakers during the live Q&A session

The availability of of biologic therapies to treat oncology disease conditions has led to improved clinical outcomes, but the high cost can create barriers and disparities in treatment access, and therefore outcomes. The use of biosimilars can improve patients' access to care by decreasing treatment costs and creating price competition between the originator product and biosimilar competitors. Watch this webinar from Clarivate on-demand now to understand the following: What is the current landscape of biosimilars in oncology? How do biosimilar approvals and market access differ between the United States and Europe? What is interchangeability and what is its impact? What are the barriers to uptake of biosimilars in oncology? What is the future of biosimilars in oncology?

Join the Pharmapack team for an interactive and informative webinar as we map out the road to the Pharmapack 2022 event, 18 & 19 May in Paris, France. This session will outline how we are preparing for the 2022 edition of the show, share key planning milestones and the measures we are taking to bring you a safe, compliant, in-person event. We will also cover the multitude of digital products, solutions and initiatives we have developed in recent months to support you in lead generation, brand visibility and business continuity. Why attend? Understand how Informa Markets is preparing for the 2022 edition of Pharmapack, hear how best to prepare your team to participate - what are the key considerations. And learn how our digital product portfolio can support your lead-gen and visibility efforts.