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Injectable Pharmaceuticals

Injectable pharmaceuticals are drug product delivery systems that can be used as an alternative to oral drugs and are more effective because of how fast they work. Injectable pharmaceuticals are passed into the human body through syringes to the bloodstream and other parts of the body. Unlike oral drugs, injectable drugs do not get dismantled in the stomach and are not altered by digestive enzymes. There are several benefits of injectable pharmaceuticals, and that is why many biotech companies and big pharmaceuticals are keying into the many opportunities in this industry.

What are the top companies that manufacture injectable pharmaceuticals?

There are many existing companies and vendors and a lot more coming up with new syringe technology ideas. Quality, financial capacity, knowledge, and experience of the industry are all key parameters in which to judge an injectable manufacturing company.

It is almost impossible to make mention of injectable pharmaceuticals without referencing Pfizer. In 2015, the company completed its buyout of Hospira, a biosimilar company and one of the top suppliers of generic injectable drugs such as anesthesia, oncology, cardiovascular, and anti-ineffective therapies.

Other big names are Hikma, Sagent and Novartis.

What are the main challenges of manufacturing injectable pharmaceuticals?

While many patients find injectable pharmaceuticals more effective than oral medicine, injectable drugs are less convenient for patients, raising issues of adherence, even for those that are in chronic conditions.

The quest for different delivery methods is another challenge even though it is being managed with the recent growth of the global injectable drug delivery market. Patients, regardless of their state, want convenience and as a result, manufacturers are faced with the challenge of meeting this demand while making sure that the right dosage form is provided.

Lack of finances can also be a significant challenge to manufacturing injectable pharmaceuticals.

What factors are driving trends in injectable pharmaceuticals?

The primary factor that appears to be driving trends in injectable pharmaceuticals is the increasing prevalence of chronic diseases. With more and more people falling ill with chronic conditions, demand for injectable drugs has increased.

Another key factor is the advancement in technology, which has contributed in no small way to patient compliance with injectable drugs.

Implementing innovations in injectable drug delivery

The biotech and pharmaceutical companies need to align their drug development with the several diseases and viruses that continue to spring up. Drug manufacturers worldwide invest a lot of money into this because it is a very long process that requires attention to details through the development, clinical trials, injection molding and approval stages. The clinical trial stage is by far the most complex of these stages because the drug has to be tested and properly evaluated to be sure it is efficient and safe for use by a large number of people.

What are the benefits of injectable pharmaceuticals?

Many people prefer to take injections than to swallow several pills, because the former are usually faster in action. Dosage of injectable drugs can be controlled: One of the significant challenges that are being faced by drug industries is drug abuse, where many use more than the prescribed amount of drug. Injectable pharmaceuticals can control this usage as professionals who are at the developing end of these pharmaceutical devices can control the quantity and concentration.

What are the limitations of injectable drug delivery devices?

The injectable drug delivery and injection molding industry is a highly innovative one, and that is why we have seen the development of many devices over the years. However, the sector still has limitations.

Recently, the injection molding industry has considered a move towards more customized hand-held devices that take advantage of existing platforms. The challenge, however, with this is the difficulty that comes with customizing the platforms. To successfully make use of these platforms, biotech and pharmaceutical companies need to differentiate them from existing ones to reach their target market faster.

Another major limitation of injectable drug delivery devices is the need for human factor engineering in designing hand-held devices. Getting the required skill on a larger scale has not been possible and has largely affected the industry projections with these devices' design. Human factor engineering is crucial for developing any connected drug delivery device in today's world. The human factor focuses on the essential elements of human interactions.

Limitation also exist in the form of regulatory guidance issued by government authorities. While the essence of these guidelines is to ensure there is a uniform framework that explains how human factor engineering and studies should be integrated into drug delivery devices, the process of seeking approval is lengthy and appears almost impossible for everyone other than the big biotech companies. This means that the availability of injectable drug delivery devices is only limited to big biotech and pharmaceutical companies' capacity.

What are some recent advances in injectable drug delivery technology?

Efforts are being made to design drug delivery devices and implement client needs into such design. An example of this is the drug delivery device of Duoject that not only focuses on meeting the mechanical needs, but has also developed a design methodology that ensures its devices are comprehensive, meeting different end-users' needs.

A notable delivery device of Duoject is its Vaccject – a cartridge-based device that serves as an alternative to the popular prefilled syringe. This delivery device comes with an auto-retract needle safety feature that can be separated from the device until you want to use it.

Another recent advancement that we have seen with injectable drug delivery technology is Enable injector development, which comes in a smaller and lighter size. It has a long-term container closure that is not contained in the device, so it is not as heavy as other devices. It also comes with a 'pause' function that users can make use of at any time and makes it possible for users to stop injecting the drug when they experience any pain or discomfort in the process.

Many biotech companies are working to deliver smarter and more effective auto-injectors. A significant consideration for the companies that produce such devices is the ability to customize an auto-injector to fit a particular company's portfolio.

Injectable pharmaceutical processing and packaging

After successfully manufacturing injectable pharmaceuticals, the next step is to have them processed and packaged. Over the years, we have seen several changes in how drugs are generally being packaged. Injectable drugs have not been different as they have come in various delivery systems that have changed over the years.

The most important elements of injectable pharmaceutical processing and packaging include the need for quality, good administration systems, and the best components. There is also the need to be aware of the regulatory guidelines that mitigate risk during packaging. Worthy of mention is the need for advanced technologies as this makes processing and packaging faster and more effective.

What materials are commonly used in injectable primary pharmaceutical packaging?

The most common primary materials used in injectable pharmaceutical packaging are prefillable glass syringes and vials for glass packaging. While these are the major materials for modern aseptic injectables, others are still being used. Some manufacturers use various glass container systems that help them customize the appearance of the injectable drug. These glass containers are used mainly for storing parenterals. Other materials needed in the packaging process include a container closure system, reconstitution kits, disposable syringes, ampoules, and pen systems.

Depending on the manufacturer and the type of design they look to achieve like plastic injection molding, they can also consider using other materials for drug delivery devices. However, it is imperative to consider end-users' needs when packaging these injectable drugs, especially because of the low compliance level of patients.


Companies (175)


Injectables Products (500+)

  • Product Prefilled Syringes

    Baxter (BioPharma Solutions) offers a wide range of traditional sterile manufacturing products which includes prefilled syringes. It offers expanded small-scale through high-volume sterile manufacturing. It can increase production potential and help ensure on-time delivery to meet product demand. By providing...
  • Product Ertapenem Inj. 1g (Injectable)

    Ertapenem for Injection is a new form of Carbapenem, which can be widely used on Gram-negative and Gram-positive anaerobes and aerobic.
  • Product Packaging and Supply Chain Solutions

    Tjoapack's packaging and supply chain solutions help our customers to make the world a healthier place. Our expert team work to facilitate your life sciences research, production and the delivery of medicines to patients across the globe.
    We offer: - Packaging solutions for; oral solid blisters and ...
  • Product Dexmedetomidine HCl Injection

    Dexmedetomide HCl is an anxiolytic, sedative, andanalgesic medication.

    Strength: 200mcg/2ml (100mcg/ml); Single-dose Vial
    This product has been approved by CFDA and US-FDA.

    Strength: 80mcg/20ml; 200mcg/50ml; 400mcg/100ml
    This product has been approv...
  • Product Sealing Solutions for Vials

    Sealing Solutions for Vials
  • Product Injectable Anaesthetics

    Sintetica SA offers wide range of products which includes injectable anaesthetics. Contact us for more information.
  • Product Antimicrobials

    Pharmaceutical Solutions Industry (PSI) offers a wide range of IV solutions which includes antimicrobials; antibiotics and antifungals. Contact us for more information.
  • Product M815 Microfluidizer® Pilot-Scale BioPharma Processor Series

    M815 Biopharma Microfluidizer® for processing clinical and production cGMP batches.  Microfluidizer® technology converts fluid pressure more efficiently into shear forces, leading industry performance standards in high-pressure homogenization.  A unique solution to maintaining consistent process pre...
  • Product CDMO Best Practices from Benches to Batches - How to Transition from Clinical to Commercial Readiness

    What you need to seamlessly transition from clinical phases to commercial readiness.

    Three unique abilities your CDMO must have to complete your project within your timeline are capability, flexibility and availability.

    August Bioservices' Director of Customer Operations, Commercial Developm...
  • Product UniSafe 1 mL

    A springless, passive safety device for 1mL pre-filled syringes, designed for simple assembly and use. Simple 2-step final assembly, Secure plunger prevents removal, spillage and repeat use. UniSafe 1mL has the following benefits:
    User confidence with an unobscured syringe barrel for full dose visibility, ...
  • Product OpHLINE - Ophthalmic Viscosurgical Devices (HA 1,4%/2%/3%)

    OpHLINE is an ophthalmic viscosurgical devise (OVD) indicated as a coadjuvant during surgical procedures, involving the anterior chamber of the eye, especially in cataract surgery, including the extraction of the lens and the insertion of intraocular lenses.
    OpHLINE is available in 3 models wit...
  • Product Injectable vials in molded glass - EasyLyo

    EasyLyo offers a stronger vial that is more resistant and
    suitable to extreme conditions encountered during the
    lyophilization process.
    EasyLyo is a range of Type I glass vials specifically
    designed to answer the growing demand for smaller
    capacity vials.

  • Product PremiumCoat® ETFE Film Components

    Aptar Pharma’s PremiumCoat® is a range of ETFE (Ethylene Tetrafluoroethylene) coated stoppers and plungers based on an approved, pure, state-of-the-art elastomeric formulation. Providing a combination of container closure integrity and improved compatibility, PremiumCoat® offers the highest standard leve...
  • Product RayDyLyo® Vial adapter

    ARaymondlife has developed the essential accessory for drug reconstitution, the vial adapter, one for each RayDyLyo diameter. The RayDyLyo® vial adapter is a medical device intended for the quick and safe reconstitution of drugs, contained in vials capped with RayDyLyo® plastic press fit caps, and ...
  • Product Molly® Autoinjector

    The Molly® and Molly® 2.25 autoinjectors feature an ultra-compact design and easy-to-use interface. Built upon a modular platform technology, Molly® meets the evolving requirements for self-injection devices, such as flexible manufacturing and customizable design options.
  • Product Injection devices

    Injection DevicesAs a world-leading medical device manufacturer, our flexible approach allows us to offer a range of customisable injectable drug delivery solutions. We keep both the end-user and pharmaceutical partner at the forefront of our products. We produce injection devices with innovative designs, to ...
  • Product Components for syringes

    Our pre-fillable syringes form a complete system when combined with the plunger rods and stoppers, the needle guard and finger rest enlargement. Especially the finger rest enlargement leads to more safety and user-friendliness. Thanks to our usability engineering, we manufacture piston rods and finger...
  • Product CordenPharma Peptides Platform

    Your Expert Partner for Peptide APIs
    • >> Proven track record delivering world class manufacturing services from early stage to commercial supply, including complex products (e.g., Linaclotide, Enfuvirtide, Mifamurtide, Eptifibatide, Glatiramer, GLP analogues). • >> Proprietary pr...

    Each vial containes 500 mg amoxicilline Na
  • Product Biolevox™ HA 2.2%

    Biolevox™ HA 2.2% is a hyaluronic acid gel for an intraarticular injections in a 2 ml pre-filled syringe. Biolevox™ HA helps to reduce pain in order to facilitate daily activities. It protects articular cartilage from further degeneration. As one of the few, it contains such high concentration of hyaluronic a...

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