IL-17 inhibitors will drive psoriatic arthritis market to $12.6 billion by 2025
The increase in diagnosed prevalent cases and the launches of interleukin (IL)-17 inhibitors, such as Eli Lilly’s Taltz and AstraZeneca’s Lumicef, will drive the market.
The psoriatic arthritis market across the seven major markets (7MM) of the US, France, Germany, Italy, Spain, the UK, and Japan, is set to grow from $4.53 billion in 2015 to around $12.6 billion by 2025, at a compound annual growth rate of 10.74%, according to research and consulting firm GlobalData.
The company’s latest report states that the relatively strong growth will primarily be driven by the increase in diagnosed prevalent cases. The launches of interleukin (IL)-17 inhibitors, such as Eli Lilly’s Taltz (ixekizumab) and AstraZeneca’s Lumicef (brodalumab), as well as Celgene’s oral therapy Otezla (apremilast), will also drive the market, and will provide more treatment options for physicians.
Alexandra Annis, MS, GlobalData’s Analyst covering Immunology, explains: “Reasons for the increased diagnosed cases of psoriatic arthritis include better awareness of the disease due to educational campaigns and an interdisciplinary approach to managing the condition between dermatologists and rheumatologists. As such, the number of total treated cases in the 7MM is expected to increase from around 770,000 in 2015 to almost 1.2 million by 2025.”
The psoriatic arthritis community has welcomed the recent approval of Novartis’ IL-17 inhibitor Cosentyx, which touts the highest clinical efficacy of any biologic yet approved. X-ray assessment data has demonstrated that 84% of patients showed no further progression of structural joint damage over two years of Cosentyx.
Annis continues: “The psoriatic arthritis market will be full of therapeutic options, with nine branded biologic drugs on the market over the forecast period. This includes the recent approvals of Lumicef and Taltz in Japan, as well as an oral systemic therapy, Otezla, and three new biologic and oral drugs in the late-stage pipeline.
“The lack of long-term efficacy for psoriatic arthritis treatments causes patients to have to cycle through the drugs. Thus, the addition of drugs with strong clinical efficacy provides a better choice of therapies for physicians and patients.”
GlobalData expects most of the current pipeline products will be launched by mid-forecast, with Lumicef and Taltz leading the way. In 2025, with all of the approved drugs trying to jockey for position and stand out among the rest, Taltz will gross an estimated $1.42 billion in total drug sales—the highest among IL-17 inhibitors. Overall, a crowded treatment space and a constant need for reduced drug costs mean new entrants will find it difficult to make an impact on the psoriatic arthritis therapy space.
Related News
-
News Eli Lilly gets ready to launch five new drugs in 2023
Eli Lilly, the American pharmaceutical company (IN, USA) are gearing up for a big year ahead, with hopes to launch five new drugs and capitalise on growing obesity and Alzheimer’s disease markets. -
News Amgen buys Horizon for $27.8 billion in bold step into the rare disease market
Amgen Inc buys pharmaceutical company Horizon Therapeutics in a multibillion-dollar deal, in hopes to capitalise on it's portfolio of drugs in the highly sort after rare disease market. -
News Pharma Supply Chain People Moves
The latest appointments and promotions across the pharmaceutical supply chain. -
News Merck to donate new Ebola vaccine to defend against outbreaks in Uganda
Pharmaceutical giant Merck has announced they will be speeding up the processing of a new vaccine against the latest strain of the Ebola virus, to be donated to a global non-profit organisation for distribution -
News CPHI Podcast Series: Driving innovation with pharmaceutical startups
The latest episode in the CPHI Podcast Series explores how startups are driving innovation by taking high-risk approaches and doing business with greater agility. -
News Greener and efficient processes: Quaternary Ammonium Salts
Quaternary Ammonium Salts play a crucial part in Organic Chemistry processes at many major industries. Discover why.
-
News Biosimilars save patients $11B annually, but barriers to adoption remain in US market
Biosimilars introduce competition into the biologics market, driving down prices and increasing patient access. -
News WHO recommends use of two monoclonal antibody treatments against Ebola
The health body recommended use of treatments by Regeneron and Ridgeback Bio
Position your company at the heart of the global Pharma industry with a CPHI Online membership
-
Your products and solutions visible to thousands of visitors within the largest Pharma marketplace
-
Generate high-quality, engaged leads for your business, all year round
-
Promote your business as the industry’s thought-leader by hosting your reports, brochures and videos within your profile
-
Your company’s profile boosted at all participating CPHI events
-
An easy-to-use platform with a detailed dashboard showing your leads and performance