Bayer Announces Results of Phase III Radium-223 Chloride Trial
The trial showed that radium-223 chloride improved overall survival in 44% of patients with castration-resistant prostate cancer and symptomatic bone metastases.
Bayer HealthCare Pharmaceuticals announced that its investigational radium-223 chloride has met the primary and secondary endpoints of a Phase III prostate cancer trial.
The randomised double-blind and placebo-controlled trial showed that radium-223 chloride improved overall survival in 44% of patients with castration-resistant prostate cancer and symptomatic bone metastases.
Radium-223 chloride demonstrated median overall survival of 14 months, compared to 11.2 months for the placebo group, a 49% improvement in time to prostate-specific antigen progression, and 33% of patients showed total alkaline phosphatise normalisation compared to 1% for placebo group.
The primary endpoint of the study wa
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