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4 Jul 2011

TAK-875 Found Effective Against Type 2 Diabetes

The study results found that all doses of the drug showed glycosylated haemoglobin reductions at week 12 versus placebo.

Japan's Takeda Pharmaceutical has received positive results from a Phase II trial of investigational compound TAK-875 which is used for the treatment of type 2 diabetes.

 

The randomised, double-blind, placebo and active (glimepiride) comparator-controlled, parallel-group and multicentre study evaluated the safety, tolerability and glycosylated haemoglobin-lowering activity of TAK-875.

 

The results found that all doses of the drug showed glycosylated haemoglobin reductions at week 12 versus placebo.

 

TAK-875, a GPR40 agonist, acts by stimulating glucose-dependent insulin secretion.

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